FOURTEENTH INTERNATIONAL PATHOGENIC NEISSERIA CONFERENCE

描述（由申请人提供）：本提案的目的是请求支持将于2004年9月5日至10日在威斯康星州密尔沃基的凯悦酒店举行的“第十四届国际致病性奈瑟氏球菌会议”。本次会议的重点是发达国家和发展中国家致病性奈瑟氏菌对公共卫生的影响，以及基础和应用研究如何有助于诊断、治疗和预防这些细菌引起的疾病。这是该领域的主要国际会议，吸引了来自30多个国家的500多名科学家和公共卫生官员。该系列的第一次会议于1978年在旧金山弗朗西斯科举行，此后每两年举行一次会议，在欧洲和北美之间交替举行。过去的会议使来自不同科学背景的科学家能够建立密切的互动关系，交流思想、专门知识和新技术。这种跨学科的合作促进了公开对话，预计第14届国际病原性奈瑟菌会议将继续这一传统。该提案要求支持20名学生、博士后研究员和年轻研究人员参加会议。 会议的具体目标是： 1.汇集来自大学，政府和生物制品行业的研究人员，他们研究淋病奈瑟菌和脑膜炎奈瑟菌以及这些病原体引起的疾病。 2.目的：探讨致病性奈瑟菌入侵和逃避宿主免疫系统的分子机制。 3.分享奈瑟氏菌基因组学的最新发展，讨论奈瑟氏菌基因表达的研究，以及进一步了解奈瑟氏菌与受感染宿主的相互作用。 4.评价预防奈瑟球菌病的新的和正在开发的疫苗和治疗方法。 5.传播有关奈瑟氏菌致病机制和流行病学监测的重要新发现，并提供信息，以通过免疫加强控制。 6.为致病性奈瑟菌的研究制定新的研究议程，并建议新的和未来的研究计划，并优先考虑这些。

DESCRIPTION (provided by applicant): The purpose of this proposal is to request support for "The Fourteenth International Pathogenic Neisseria Conference" which will be held September 5-10, 2004 at the Hyatt Regency Hotel in Milwaukee, Wisconsin. The emphasis of this Conference is the public health impact of the pathogenic Neisseria in both developed and developing countries, and how basic and applied research are contributing to the diagnosis, treatment, and prevention of diseases caused by these bacteria. This is the major international conference in the field that attracts over 500 scientists and public health officials from over 30 countries. The first conference in the series was held in 1978, in San Francisco and conferences have been held every two years since then, alternating between Europe and North America. The conferences in the past have allowed for the establishment of close interactions among scientists from different scientific backgrounds for an exchange of ideas, expertise, and new technologies. Such interdisciplinary collaborations have fostered open dialogues and it is expected that the 14th International Pathogenic Neisseria Conference will continue in this tradition. This proposal requests support for 20 students, postdoctoral fellows and young investigators to attend the conference. The Specific Aims of the meeting are: 1. To bring together investigators from universities, governments and the biologics industry who study Neisseria gonorrhoeae and Neisseria meningitidis and the diseases that these pathogens cause. 2. To assess the current studies on the molecular mechanisms by which the pathogenic Neisseria are able to invade and evade the host immune system. 3. To share new developments in neisserial genomics and to discuss studies of gene expression and further understanding of interactions of Neisseria with infected hosts. 4. To evaluate new and developing vaccines and treatment to prevent neisserial disease. 5. To disseminate important new findings concerning the pathogenic mechanisms and epidemiological surveillance of Neisseria and provide information to improve control through immunization. 6. To develop new research agenda for the study of the pathogenic Neisseria and to recommend new and future research initiatives and prioritize these.