2004 Microbial Stress Response Gordon Conference

描述（由申请人提供）：本提案要求为将于2004年7月11日至7月16日在霍利奥克山学院举行的微生物应激反应戈登研究会议提供部分支持。这次会议非常成功，是唯一一次广泛考虑原核生物中所有应激表现的会议，包括特定的应激反应、发育和发病机制。会议还考虑了真核微生物的相关应激反应。这次会议的优势在于，它汇集了来自相关但通常不相交领域的前沿研究，从而使思想相互交融。会议的建议会议是：1 -氧化应激，II-宿主病原体相互作用；三世——原核的发展;四、小rna在感知和调节应激中的作用；V——应激和发育中的蛋白水解；Vl——信号传导的计算和基因组方法；第七,微生物生态学/多样性;八、应激反应基因表达的信号转导途径；IX-感知生长阶段。目前的会议包括对金属在应激反应中的相当大的讨论，并扩大了对基因组分析和建模的强调。通过将计算科学家和实验学家聚集在一起，我们希望在这个不断扩大的领域建立未来的合作。作为这次会议威望的一个指标，我们注意到会议主席包括许多原核生物学的主要人物。每次会议将有几位特邀演讲者和一些从摘要中选择的演讲者。我们今年的演讲者包括女性、少数族裔和新教员。参与者通常包括：主要来自大型研究机构的新老教员，但也有相当数量的来自小型文理学院的教员、工业界的科学家、博士后研究员和学生。这次会议普遍超额认购，鉴于目前的计划，可能会有非常广泛的吸引力。

DESCRIPTION (provided by applicant): This proposal requests partial support for a Gordon Research Conference on The Microbial Stress Response to be held from July 11 to July 16, 2004 at Mt. Holyoke College. This extraordinarily successful meeting is the only one that broadly considers all manifestations of stress in prokaryotic organisms, including specific stress responses, development and pathogenesis. The meeting also considers relevant stress responses in eukaryotic microbes. The strength of this meeting is that it brings together cutting edge research from related but often non-intersecting fields to allow cross-fertilization of ideas. The proposed sessions for the meeting are: I--Oxidant stresses, II--The Host pathogen interaction; III--Prokaryotic development; IV--Small RNAs in sensing and regulating stress; V--Proteolysis in stress and development; Vl--Computational and genomic approaches to signaling; VII--Microbial ecology/diversity; VIII--Signal transduction pathways in stress responsive gene expression; IX--Sensing growth stages. The current meeting includes a sizeable discussion of metals in stress responses and features an expanded emphasis on genomic analysis and modeling. By bringing together computational scientists with experimentalists, we expect to nucleate future collaborations in this expanding area. As one indicator of the prestige of this meeting, we note that session chairs include many of the major figures in prokaryotic biology. Each session will have several invited speakers and some speakers chosen from the abstracts. Our speakers this year include women, minorities and new faculty. Participants generally include: new and established faculty mostly at major research institutions, but with a sizeable representation of those from small liberal arts colleges, scientists in industry, postdoctoral fellows, and students. This meeting is generally oversubscribed and given the current program is likely to have very wide appeal.