Bacterial Cell Surfaces Gordon Conference

描述（由申请人提供）：本提案申请支持第16届细菌细胞表面戈登会议，该会议将于6月27日至7月2日在新罕布什尔州新伦敦的Colby-Sawyer学院举行。本次会议的传统重点是细菌膜的结构和功能，包括发病机制、抗生素耐药性和膜转运等主题，这些将继续是下次会议的中心主题。借助膜蛋白的高分辨率结构数据，如AcrB多药物外排转运体、BtuCD ABC atp酶、Lac渗透酶、电压门控钾通道和GIpF水甘油三酯oporin， 2004年会议将成为讨论获得的完整膜蛋白机制信息的主要平台。此外，这次会议将扩展到生物恐怖主义和抗生素耐药性领域，2004年将发表关于毒素、噬菌体裂解酶的功能、结构和调节的报告，并详细讨论β -内酰胺酶。因此，建议的会议应实现介绍分子微生物学领域的前沿研究的目标。

DESCRIPTION (provided by applicant): This proposal applies for support for the 16th Bacterial Cell Surfaces Gordon Conference, to be held from June 27 to July 2 at Colby-Sawyer College in New London, New Hampshire. The traditional focus of this meeting is on the structure and function of bacterial membranes, including such topics as pathogenesis, antibiotic resistance and membrane transport, and these continue to be central themes in the next conference. Aided by high-resolution structural data on membrane proteins such as the AcrB multidrug efflux transporter, the BtuCD ABC ATPase, the Lac permease, the voltage-gated potassium channel and the GIpF aquaglyceroporin, the 2004 Conference will become a major platform for the discussion of mechanistic information obtained on integral membrane proteins. In addition, this meeting will expanded into the areas of bioterrorism and antibiotic resistance, with presentations in 2004 on the function, structure and regulation of toxins, phage lytic enzymes, and detailed discussions of beta-Iactamases. The proposed meeting should thus accomplish the goal of presenting the cutting-edge research in the area of molecular microbiology. The participants at the Bacterial Cell Surfaces Gordon Conference include the leaders in this field, drawn from academics, government and industry, as well as more junior scientists, including many graduate students and postdoctoral fellows who represent the future of this area. A major use of the support sought in the current application is to assist such junior people in participating in this meeting. The Gordon Conference is organized to maximize the opportunity for discussion and for the presentation of the latest findings in this area, with poster sessions occurring every afternoon and discussion periods after each formal session.