Exploring and exploiting novel therapeutic avenues in mesothelioma

间皮瘤是一种致命的肺癌。它迅速生长并侵入胸腔等周围组织，导致严重的呼吸急促和疼痛。化疗的效果有限，尽管免疫疗法看起来很有希望，但大多数患者没有反应。我将调查间皮瘤为什么如此具有侵袭性；如何提高对免疫治疗的反应，以及如何最好地将化疗和免疫治疗结合起来。我的目标是开发新的治疗方法，使间皮瘤患者受益。

Mesothelioma is a fatal cancer of the lungs. It rapidly grows and invades surrounding tissues such as the ribcage, causing severe shortness of breath and pain. Chemotherapy has limited effect and although immunotherapy appears promising, most patients do not respond. I will investigate why mesothelioma is so invasive; how to improve the response to immunotherapy and how to best combine chemotherapy and immunotherapy. I aim to develop new treatments that will benefit patients with mesothelioma.