Intravitreal Corticosteroid for Macular Edema Study

描述(由申请人提供)：威斯康星大学眼底照片阅读中心(UW FPRC)建议作为玻璃体内皮质类固醇黄斑水肿研究的照片阅读中心。为达致这个目标，我们建议： 1.应用现有的记录和分级黄斑水肿的程序。我们可以提供黄斑水肿成像方案(彩色立体眼底照片、荧光素血管成像和光学相干断层扫描)，并在定位、认证和反馈临床摄影师方面经验丰富。通过扩展早期治疗糖尿病视网膜病变研究分类，我们有了从彩色照片和荧光素血管造影评估/分级黄斑水肿的方案。我们正在制定一项评估OCT扫描的方案。 2.协助研究主席和研究调查人员1)进行临床试验(例如，及时审查照片和血管造影术是否合格)，2)分析结果数据，3)准备出版手稿。 UW FPRC首席调查员和工作人员在参与合作方面经验丰富 多中心临床试验，并致力于糖尿病和视网膜静脉阻塞引起的黄斑水肿的新疗法的研究。

DESCRIPTION (provided by applicant): The University of Wisconsin Fundus Photograph Reading Center (UW FPRC) proposes to serve as photograph reading center for the Intravitreal Corticosteroid for Macular Edema study. To accomplish this, we propose to: 1. Apply current procedures for documenting and grading macular edema. We can provide protocols for macular edema imaging {color stereoscopic fundus photographs, fluorescein angiograms, and optical coherence tomograms), and are experienced at orienting, certifying, and giving feedback to clinic photographers. By extending the Early Treatment Diabetic Retinopathy Study classification, we have protocols for evaluation/grading of macular edema from color photographs and fluorescein angiograms. We are developing a protocol for assessment of OCT scans. 2. Assist the study chair and study investigators in 1) the conduct of the clinical trial (for example, timely review of photographs and angiograms for eligibility), 2) the analysis of the resultant data and 3) the preparation of manuscripts for publication. The UW FPRC principal investigator and staff are experienced at participation in collaborative multi-center clinical trials and are strongly committed to the study of new treatments for macular edema due to diabetes mellitus and retinal vein occlusion.