Training Program in Hematopoietic Cell Transplantation

超出提供的空间。这项资助申请中描述的计划将培训博士后研究员，为其在学术造血细胞移植领域的职业生涯做准备。这一培训计划具有独特的造血干细胞移植和相关科学的重点。完成内科、血液学或肿瘤学培训的拥有医学博士或医学博士学位的候选人将被考虑参加为期三年的培训计划。第一年的培训计划包括为期六个月的临床造血细胞移植强化经验。在这一初始阶段，受训者将接触到各种造血细胞移植，包括亲属和非亲属捐赠者的自体和异体移植。学员的体验将集中在斯坦福大学医学中心的骨髓移植单元EL。此外，还将提供在骨髓移植日医院和斯坦福大学医疗中心诊所的门诊经验，在那里将指导受训者如何正确选择移植患者、移植患者的咨询和替代治疗以及门诊环境中复杂患者的管理。受训者还将在骨髓移植临床实验室轮换一个月，在那里他们将学习冷冻保存、移植操作、质量控制和其他与移植患者操作干细胞产品相关的技术。将提供生物伦理学、临床试验设计和解释以及统计学方面的正式指导。课程内容包括免疫学、遗传学和细胞生物学。完成临床轮换后，实习生将花大约两年半的时间与一名教员进行深入学习。这些教职员工的研究重点是造血细胞移植的基础科学和临床应用。丰富的实验室经验将为学员在学术造血细胞移植领域的职业生涯做好准备。此外，受训人员将负责执行一项临床方案，该方案正在进行中，或与骨髓移植系的一名成员协商后制定。在培训结束时，个人将为成为一名在造血细胞移植基础和临床领域进行了充分研究的独立调查员做好职业准备。关键人员========================================Section End===========================================

EXCEED THE SPACE PROVIDED. The program described in this grant application will train post-doctoral fellows for a career in academic hematopoietic cell transplantation. This training program has a unique focus of hematopoietic stem cell transplantation and related sciences. Candidates with either a M.D.or M.D./Ph.D. degrees who have completed training in internal medicine and either hematology or oncology will be considered for the three- year training program. The first year of the training program includes an intensive six-month experience in clinical hematopoietic cell transplantation. During this initial phase, trainees will be exposed to the full spectrum of hematopoietic cell transplantation including autologous and allogeneic transplantation from related and unrelated donors. The trainees' experience will be centered on the Bone Marrow Transplant Unit, El, at Stanford University Medical Center. In addition, out-patient experience in the Bone Marrow Transplant Day Hospital and clinics at Stanford University Medical Center will be provided where trainees will be instructed on the appropriate selection of patients for transplantation, counseling of the transplant patient and alternative treatments as well as the management of complex patients in an outpatient setting. The trainees will also rotate through the Bone Marrow Transplantation clinical laboratory for a one month period where they will be introduced to methodologies of cryopreservation, graft manipulation, quality control, and other techniques relevant to the manipulation of stem cell products for the transplant patient. Formal instruction in bioethics, clinical trial design and interpretation, and statistics will be provided. Course work in immunology, genetics and cell biology will be offered. Following completion of the clinical rotations, trainees will spend approximately two and one half years of in-depth study with a member of the faculty. These faculty members are individuals whose research focuses on the basic science and clinical application of hematopoietic cell transplantation. Intensive laboratory experience will prepare the trainee for a career in academic hematopoietic cell transplantation. In addition, the trainees will be responsible for the conduct of a clinical protocol which is either on-going or developed in consultation with a member of the Bone Marrow Transplantation Division faculty. At the conclusion of their training, individuals will be prepared for a career as an independent investigator well-studied in the basic and clinical areas of hematopoietic cell transplantation. KEY PERSONNEL ========================================Section End===========================================