Animal and ABSL III

动物模型的分析是复杂和劳动密集型的。这个小鼠动物生物安全3级核心(核心A)旨在为需要增加劳动力的实验过程中的所有项目提供劳动力。一个平稳运行的ABSL 3对这个项目至关重要，这个核心将负责维护ABSL及其设备。 该项目中的ABSL III设施实际上是一个能够在其中进行动物和细胞培养实验的联合实验室。虽然每个项目都有自己的人员专注于特定项目的目标，但项目的维护、维护和劳动强度需要额外的人员，以确保核心实验室保持在高水平，并协助进行劳动密集型动物模型和器官收集。有许多方法特别与动物实验有关，这些方法在不同的项目之间重叠。因此，有两名有经验的人员在关键时间进入动物实验将既划算又高效，并保持动物实验的质量控制。核心A的作用是：目标1.维护库存和接种程序，以维持可重现的模型。目标2.在ABSL 3实验室内保持良好的生物安全性，并选择试剂状态。目标3.在项目1、2和3中，协助分配给动物实验劳动密集型部分项目的技术人员。

The analyses of animal models is complex and labor intensive. This Murine Animal Biosafety Level 3 Core (Core A) is designed to provide labor to all of the projects during experimental procedures that require an increased labor force. A smoothly operating ABSL 3 is critical to this program project and this core will be responsible for maintaining the ABSL and its equipment. The ABSL III facility in this program project is actually a combination lab capable of performing animal and cell culture experiments in it. While each of the projects has its own personnel to concentrate on the goals of that particular project, the maintenance, upkeep and labor intensity of the projects requires additional personnel that can assure that this core lab is maintained at a high level and assist with the labor intensive animal models and organ collection. There are many methods particularly related to the animal experiments that overlap among the different projects. Therefore having two experienced personnel that can enter into the animal experiments at critical times will be both cost effective and efficient as well as maintain quality control among the animal experiments. The role of Core A is: Aim 1. Maintain stocks and inoculation procedures to maintain reproducible models. Aim 2. Maintain compliance within the ABSL 3 lab for excellent biosafety and select agent status. Aim 3. Assist technicians assigned to projects in the labor intensive portion of animal experiments in Projects 1, 2 and 3.