Therapeutic Intermittent Hypoxia effects on neurovascular health and metabolism.

这一博士项目旨在研究两种治疗干预措施(轻度间歇性低氧和通过运动产生的轻度生理压力)，以在一生中保持认知功能。由于拟议的干预保护机制涉及大脑新陈代谢和脑血管反应的类似变化，该项目将利用多模式成像技术(磁共振成像、经颅多普勒超声和近红外光谱)来表征这些拟议的大脑变化，以及这些变化可能如何与认知功能的改善有关。

This PhD project aims to investigate two therapeutic interventions (mild intermittent hypoxia and mild physiologic stress through exercise) to maintain cognitive function across the lifespan. As the proposed protective mechanisms for the intervention involves similar changes to brain metabolism and cerebrovascular responses, the project will utilise multi-modal imaging techniques (magnetic resonance imaging, transcranial doppler ultrasound and near infrared spectroscopy) to characterise these proposed brain changes, and how these may relate to improvements in cognitive function.