How alphaviruses cause disease and identifying new therapeutics.

甲型病毒通过蚊子传播，会导致各种严重的人类感染。这个项目调查甲型病毒是如何致病的，特别关注炎症性肌肉骨骼疾病。预期的结果是更好地了解人类病毒性疾病，以期改进预防和治疗战略，以减少甲型病毒和相关病毒的疾病负担。该研究战略是世界第一的，该研究所在这一领域处于国际领先地位。

Alphaviruses are transmitted by mosquitoes and cause a variety of serious human infections. This project investigates how alphaviruses cause disease, with special focus on inflammatory musculoskeletal diseases. The expected outcomes are a better understanding of human viral diseases, with a view to improving prevention and treatment strategies to reduce the disease burden of alphaviruses and related viruses. The research strategy is a world-first, and the institute is an international leader in this area.