Course Development in the Neurobiology of Disease

描述(由申请人提供)：本提案是为在贝勒医学院(BCM)建立新的疾病神经生物学课程和研究生学习轨迹而提供规划支持。BCM在神经科学基础和临床研究方面有着悠久的卓越历史。该计划代表着一项新的努力，旨在开发研究生教育中的综合课程和培训轨道，利用来自10个基础和临床部门的教师的优势，提供一门正式的课程，其中包括详细的第一原理方法，研究影响神经系统的疾病的潜在细胞和分子过程。这项合作努力从神经学、神经外科、儿科、精神病学和特殊感官(眼科学和耳鼻喉科)领域对疾病的病理生物学进行严格科学分析的角度来研究神经系统。该计划将从现有的神经科学研究生项目(目前由NIH NIGMS Ruth L.Kirschstein NRSA T32博士资助，资助至2009年)、医学博士/博士项目以及贝勒医学院新成立的转化生物学和分子医学研究生培训项目，以及为其他对分子和细胞生物学、发育生物学和遗传学研究生项目感兴趣的学生提供进入疾病的神经生物学课程的机会。课程将包括基础和临床神经学家的团队讲座，以及通过查房和访问神经科学临床诊断和治疗程序接触临床病例。此外，这门课程将作为现有神经科学研究生课程的标准组成部分，面向所有神经科学专业的学生，并为计划将研究培训主要集中在疾病神经生物学的学生提供一个焦点。这一倡议是在BCM特别幸运的时候制定的，同时启动了一项重大战略计划，其中包括翻译神经科学，聘请了一名新的神经科学教席，任命了学院第一位主任，负责协调基础系和临床系之间的神经科学倡议，并扩大了翻译生物学方面的研究生培训计划。

DESCRIPTION (provided by applicant): This proposal is for planning support to establish a new neurobiology of disease course and track of graduate study at Baylor College of Medicine (BCM). BCM has a long history of excellence in neuroscience research - both basic and clinical. This program represents a new effort to develop an integrated course and training track in graduate education that draws on the strengths of faculty from 10 basic and clinical departments, providing a formal course that includes a detailed first principles approach to the study of the underlying cellular and molecular processes of diseases that affect the nervous system throughout the lifespan. The collaborative effort approaches the study of the nervous system from the perspective of rigorous scientific analysis of the pathobiology of disorders from the realms of Neurology, Neurosurgery, Pediatrics, Psychiatry and the special senses (Ophthalmology and Otolaryngology). The program will draw students from existing graduate programs in Neuroscience (currently supported by an NIH NIGMS Dr. Ruth L. Kirschstein NRSA T32 training grant that is funded until 2009), the M.D./Ph.D. program and the newly formed Translational Biology and Molecular Medicine graduate training program at Baylor College of Medicine, as well as providing access to the neurobiology of diseases course to other interested students from graduate programs in molecular and cellular biology, developmental biology and genetics. The course will include team lectures from basic and clinical neuroscientists as well as exposure to clinical cases through rounds and visits to neuroscience clinical diagnostic and therapeutic procedures. In addition, the course will serve as a standard component of the existing Neuroscience graduate curriculum for all neuroscience students as well as providing a focal point for students who plan to focus their research training primarily in neurobiology of disease. This initiative is being developed at a particularly auspicious time at BCM, in conjunction with the launching of a major strategic plan that includes translational neuroscience, the hiring of a new Chair of Neuroscience, the appointment of the College's first Director for coordinating Neuroscience Initiatives between basic and clinical departments and expanded graduate training initiatives in translational biology.