Internet Use and Informed Consent

说明： 申请者是癌症中心的博士后研究员，即将晋升到生物伦理系的初级教员职位。这一KO1奖项预计将有助于转移申请者的研究重点，并提供生物工程学方面的额外培训，特别是知情同意和与互联网相关的研究和创新。申请者的职业目标是发展成为生物伦理学和知情同意领域的独立调查员。他的具体目标是：(1)推进规范和理论生物伦理学领域的培训；(2)作为经验研究人员完成培训，包括高级统计方法，特别是应用于生物伦理学；(3)发展国际生物伦理学的工作能力；(4)获得作为行为干预者的培训和经验；以及(5)开发一项知情同意研究计划，这将导致他的第一个研究者发起(RE1)奖。申请人提议一个为期五年的培训计划，由强大的生物伦理学研究部门的教员和一名互联网研究方面的领先专家组成。他的赞助人是一位非常有经验的生物伦理学研究人员，他的工作重点是癌症患者之间的知情同意、沟通和决策。共同赞助人和导师代表与申请者的研究和职业发展计划直接相关的子专业部门。职业发展计划描述了专注于增强申请者在上述五个领域的知识和专长的活动。这些活动包括生物伦理学和知情同意基础的正规课程工作、统计方法和行为干预方面的研究培训、国际生物伦理学和互联网健康研究的独立阅读，以及作家讲习班。申请人提议的研究将涉及四项连锁研究，旨在了解互联网在癌症临床试验知情同意过程中的作用和影响。这些措施包括：(1)文献和网站综述；(2)对接受随机临床试验的患者的调查；(2)对肿瘤学家和研究人员的调查；以及(4)旨在 对患者在知情同意过程中使用互联网的RO1行动研究的基础。这项研究的结果预计将大大提高考虑将临床试验作为治疗选择的个人对互联网使用的理解和使用前景。

DESCRIPTION: The applicant is a post-doctoral fellow in the Cancer Center who is advancing to a junior faculty position in the Department of Bioethics. This KO1 award is expected to help transition the focus of the applicant's research and to provide additional training in biocthics, particularly informed consent and Internet-related research and innovation. The applicant's career goal is to develop into an independent investigator in bioethics and informed consent. His specific objectives are to:(1)advance training in the area of normative and theoretical bioethics; (2) complete training as an empirical researcher, including in advanced statistical methods, specifically as applied to biocthics; (3) develop capacity to work in international bioethics; (4) obtain training and experience as a behavioral interventionist; and,finally, (5) develop a research program in informed consent that will lead to hisfirst investigator-initiated (Re1) award.The applicant proposes a five-year training program with faculty members from a strong bioethics research department, and with a leading expert in Internet-focused research. His sponsor is a very experienced bioethics researcher whose work has focused on informed consent communication and decision making among cancer patients. Co-sponsors and mentors represent subspecialty divisions that are directly relevant to the applicant's research and career development plan.The career development plan describes activities focused on enhancing the applicant's knowledge and expertise in the five areas described above. These activities include ormal course work in the foundations of bioethics and informed consent, research training in statistical methods and behavioral interventions, independent reading in international bioethics and Internet health studies, and a Writer's Workshop. The applicant's proposed research will involve four interlocking studies aimed at understanding the role and impact of the Internet in the informed consent process for cancer clinical trials. These include:(1) a literature and websitereview; (2) a survey of patient subjects who have been offered a randomized clinical trial; (2) a survey of oncologist-investigators; and, (4) a pilot intervention aimed at laying the groundwork for an RO1 action-based study of patient Internet use during the informed consent process. Findings from the research are expected to substantially improve understanding of Internet use and prospects for use among individuals considering a clinical trial as a treatment option.