CORE--ANIMAL HISTOPATHOLOGY

动物组织病理学核心设施的目标是为用户提供可靠、高质量和具有成本效益的组织病理学服务，并为调查人员提供获得委员会认证的兽医病理学家的机会。服务包括石蜡切片的制备、组织化学染色、低温冷冻切片的制备、尸检技术和组织病理学分析的咨询和培训，以及为调查人员提供专用设备。该中心由Virginia Godfrey， DVM, Ph.D .， ACVP领导，指导老师是David Lee博士。动物组织病理学核心支持大量

The goals of the Animal Histopathology Core facility are to provide users with reliable, high quality, and cost-effective histologic services and to give investigators access to a board-certified veterinary pathologist Services include preparation of paraffin sections, histochemical staining, preparation of cryostat frozen sections, consultation and training in necropsy techniques and histopathologic assays, and provision of specialized equipment for use by investigators. The Core is directed by Virginia Godfrey, DVM, Ph.D, ACVP and the Faculty Advisor is Dr. David Lee. The Animal Histopathology Core supports a large number of Center members who use the mouse as a model system. Highlights of research supported by the Core include: analysis of knockout mice lacking CDKIs p18 and p27 by Dr. Yue Xiong (Cancer Cell Biology) and discovery of WT2 tumor suppressor gene by Dr. Bemard Weissman (Cancer Genetics). Future plans for the Core include access to another veterinary pathologist through interaction with the Mutant Mouse Regional Resource Center (MMRRC) and addition of limited immunohistochemistry services.