Core--Human Tissue and Pathology- Shared Resource

十多年来，人体组织和病理学核心一直是KCI的重要设施。核心为KCI的研究人员提供了数千份研究所需的人体组织样本。核心机构负责在人类调查委员会和HIPPA的既定规则范围内，为调查目的采集、储存和转移新鲜和冷冻人体组织样本。此外，完整和准确的病理诊断，包括分期和分级参数可用于子集的集合;辅助研究进行，并可访问。这些功能最近随着激光显微切割系统和组织的获得而扩展。 微阵列构建设备和纳入额外的服务，例如通过诊断类别识别病例，并能够从病理部门文件中检索病理材料，组织学处理，免疫组织化学和原位杂交。在蛋白酶和癌症，乳腺癌，发育治疗学，流行研究和预防，分子生物学和人类遗传学计划的多个资助的研究人员利用核心的服务，并与核心研究人员进行科学合作。

The Human Tissue and Pathology Core has been an essential facility of the KCI for more than a decade. The Core provides investigators in the KCI with thousands of human tissue samples necessary for research purposes. The Core facility is charged with harvest, storage, and transfer of fresh and frozen human tissue samples for investigative purposes, within the established rules of the Human Investigation Committee and HIPPA. In addition, a complete and accurate pathological diagnosis including staging and grading parameters is available for subsets of the collection; ancillary studies are performed and are accessible. These functions have expanded recently with the acquisition of a laser microdissection system and tissue microarray construction equipment and the incorporation of additional services such as case identification by diagnostic categories with the ability to retrieve pathology material from Pathology Department files, histology processing, and immunohistochemistry and in situ hybridization. Multiple funded investigators in the Proteases and Cancer, Breast Cancer, Developmental Therapeutics, Popluation Studies and Prevention, and Molecluar Biology and HumanGenetics Programs utilize the services of the Core and have scientific collaborations with Core investigators.