RAND COORDINATING CENTER: SEXUAL DIFFUSION OF HIV STUDY

描述(由申请人提供)： 在这项提案中，我们提出了我们的艾滋病毒性行为获取和传播合作协议方案协调中心(SATH-CAP)的概念，以支持多学科研究，寻求更好地了解艾滋病毒在吸毒人群亚群内和跨吸毒人群以及向非吸毒人群的性传播。对于这一具有挑战性的努力，我们带来了对其重要性的坚定信念；在相关领域的丰富实质性经验；通过建立共识的进程管理大规模、多地点研究的专门知识；就这一专题制定和开展研究的丰富经验；高超的数据收集和数据管理能力；以及作为研究人员进行“协调”的经验。我们还带来了承担这项工作的强烈愿望和完成这项工作的意愿。为此，我们提出了以下具体目标：具体目标1：与研究中心和NIDA协作改进方法和设计；具体目标2：协助指导委员会制定和实施SATH-CAP合作多中心项目组成部分(即吸毒和性危险行为的艾滋病毒行为流行病学)；具体目标3：协调SATH-CAP指导委员会、小组委员会和工作组会议的后勤职能，包括制作和分发委员会议程、背景材料和会议记录；具体目标4：开发和维护一个SATH-CAP网站，以便利传播易于使用的项目管理工具(如进度报告表等)；具体目标5：协助各研究中心进行数据质量控制检查，包括数据收集方面的现场培训，并协助数据管理和分析，包括实施多中心数据管理系统，以促进多中心协作工作；具体目标6：促进跨中心数据可比性，作为本次合作研究收集的数据的储存库，并编制公共使用数据集；具体目标7：按照指导委员会即将制定的程序，协助编写出版物。

DESCRIPTION (provided by applicant): In this proposal, we present our concept of a Coordinating Center for the Sexual Acquisition and Transmission of HIV Cooperative Agreement Program (SATH-CAP) to support multi-disciplinary research that seeks to better understand the sexual transmission of HIV within and across drug-using population subgroups and to non-drug using populations. To this challenging effort, we bring a strong belief in its importance; rich substantive experience in the relevant areas; expertise in managing large scale, multi-site research studies by a process of consensus building; extensive experience in formulating and carrying out research on this topic; superb data collection and data management capabilities; and experience as researchers with being "coordinated". We also bring a strong desire to take on the work and a willingness to see it through to completion. To this end, we propose the following specific aims: Specific Aim 1: Collaborate with Research Centers and NIDA in the refinement of methods and designs; Specific Aim 2: Assist the Steering Committee in developing and implementing the SATH-CAP cooperative multi-center project component (i.e., the HIV behavioral epidemiology of drug use and sexual risk behaviors); Specific Aim 3: Coordinate logistical functions of meetings of the SATH-CAP Steering Committee, subcommittees, and workgroups, including production and distribution of committee agendas, background materials, and minutes; Specific Aim 4: Develop and maintain a SATH-CAP website to facilitate dissemination of easily accessible project management tools (e.g., progress report forms etc.); Specific Aim 5: Assist Research Centers with data quality control checks, including on-site training for data collection, and assist in data management and analysis, including implementing multi-Center data management systems to facilitate multi-Center collaborative work; Specific Aim 6: Facilitate cross-center data comparability, serve as a repository for data collected under this cooperative study, and prepare public use data sets; Specific Aim 7: Assist in development of publications, in accordance with Steering Committee procedures to be developed.