Psychological Distress and Cancer Survival: Interplay between Psychosocial, Socioeconomic, Biological and Behavioural factors.

心理压力越大，癌症存活率越低。然而，心理痛苦与癌症存活率之间的联系机制尚不清楚。此外，许多基于人群的研究表明，较低的社会经济地位(SES)会增加心理困扰对各种原因和心血管疾病(CVD)死亡率的影响。然而，尚不清楚SES是否缓和了痛苦和癌症存活率之间的联系。因此，本博士论文旨在阐明(1)心理困扰与癌症存活率之间的生物行为机制，以及(2)SES在心理困扰与癌症存活率之间的调节作用。

Greater psychological distress has been associated with poorer cancer survival. However, the mechanisms linking psychological distress and cancer survival are unknown. Furthermore, many population-based studies show that low socioeconomic status (SES) augments the effects of psychological distress on all-cause and cardiovascular disease (CVD) mortality. However, it is unknown whether SES moderates the association between distress and cancer survival. Therefore, this PhD aims to elucidate (1) the biobehavioural mechanisms linking psychological distress and cancer survival, and (2) the moderating role of SES in the association between psychological distress and cancer survival.