Export of effector proteins by P. falciparum to the infected erythrocyte.

疟疾寄生虫的感染对人类有致命的后果。为了生存，寄生虫会输出数百种蛋白质来占领红细胞。已经确定了一种介导这种出口的易位子，重要的问题仍然没有答案。在这项研究中，我的目标是确定蛋白质输出到红细胞（EXP2）的主要易位子组件之一的功能，并通过这个过程确定它是否是抗疟疾药物开发的可行目标。

Infection by the malaria parasite has lethal consequences for humans. In order to survive the parasite exports hundreds of proteins to commandeer the erythrocyte. A translocon that mediates such export has been identified and important questions remain unanswered. In this research, I aim to determine the function of one of the major translocon components for export of proteins to the erythrocyte (EXP2) and through this process determine if it is a viable target for anti-malarial drug development.