Extinguishing fearful and addictive brain during adolescence
Extinguishing fearful and addictive brain during adolescence
批准号:
nhmrc : 1083309
负责人:
Dr Jee Hyun Kim
金额:
$28.57万
依托单位国家:
澳大利亚
项目类别:
Career Development Fellowships
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2019-12-31
中文摘要
暴露疗法依赖于对先前触发因素的情绪减少,因为在安全的环境中暴露于这些触发因素而没有情绪事件。由于前额皮质中不同受体的不平衡,青春期标志着一段对这类治疗特别有抵抗力的成熟时期。我们会使用现有的经临床批准的药物来纠正这种化学失衡,并促进行为疗法来治疗青少年焦虑和药物滥用。
英文摘要
Exposure therapies rely on the decrease in emotions to previous triggers due to the exposure to those triggers without an emotional event in a safe environment. Adolescence marks a period of maturation that is particularly resistant to such therapies, due to the imbalance of different receptors in their prefrontal cortex. We will redress such chemical imbalance by using existing clinically-approved drugs, and facilitate behavioural therapies to treat adolescent anxiety and substance abuse.
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会议论文
Preclinical investigation into novel therapeutics to treat drug abuse during adolescence and adulthood
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批准号:nhmrc : 1063140
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项目类别:Project Grants
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资助金额:$47.59万
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财政年份:2014
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负责人:Dr Jee Hyun Kim
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依托单位:
The role of the mGlu5 receptor in extinction
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批准号:nhmrc : 1022201
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项目类别:Project Grants
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资助金额:$40.1万
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财政年份:2012
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负责人:Dr Jee Hyun Kim
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依托单位:
海外基金