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Studies Of Thyroid Diseases

Studies Of Thyroid Diseases
甲状腺疾病的研究
批准号:
6983903
负责人:
Ira W. Levin
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
罗宾斯博士参与了NCI项目,研究切尔诺贝利核电反应堆事故对甲状腺的影响。这项关于白俄罗斯儿童罹患甲状腺癌的病例对照研究已发表在《辐射研究》杂志上,该研究表明I-131估计的甲状腺辐射剂量与癌症之间存在明显的关系。对白俄罗斯和乌克兰儿童队列的前瞻性研究目前正在这两个国家进行,明斯克、戈梅尔和基辅的筛查正在进行中。已经完成了两个两年一次的筛查周期,目前正在分析第一个周期中的甲状腺结节疾病的流行情况。甲状腺辐射剂量的重建正在平行进行。终点包括甲状腺肿瘤,包括良性和恶性,甲状腺自身免疫性疾病和甲状旁腺功能亢进症。举办了一次关于缺碘对甲状腺癌风险的潜在影响的研讨会,并发表在《甲状腺》杂志上。该队列研究的设计和方法已发表在《辐射研究》杂志上。
英文摘要
Dr. Robbins participates in the NCI project studying the thyroid effects of the nuclear power reactor accident in Chernobyl. The case-control study on children in Belarus who developed thyroid cancer has been published in Radiation Research, and demonstrated a clear relationship between the estimated thyroid radiation dose from I-131 and the cancers. The prospective study of cohorts of children in Belarus and Ukraine is now proceeding in both countries and screening is under way in Minsk, Gomel and Kiev. Two biennial screening cycles have been completed and the prevalence of thyroid nodular disease in the first cycle is now being analyzed. Reconstruction of the thyroid radiation dose is proceeding in parallel. The end points include thyroid neoplasia, both benign and malignant, thyroid autoimmune disease, and hyperparathyroidism. A workshop on the potential effect of iodine deficiency on thyroid cancer risk was held and was published in Thyroid. The design and methods of the cohort study have been published in Radiation Research.
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