Research Training in Disability & Disabling Disorders

描述（由申请人提供）： 这个以病人为导向的研究的中期职业研究者奖的具体目标是：（1）进一步建立候选人的独立的以病人为导向的研究计划，在流行病学和预防社区生活的老年人残疾;和（2）建立一个正式的导师计划，初级研究人员，跨学科，谁是追求以病人为导向的老龄化研究有关残疾和致残性疾病。这包括一般的功能评估以及高度流行的疾病特异性病症的功能后果，如关节炎、心脏病、糖尿病、中风、癌症、抑郁症和痴呆症。候选人的最终目标是建立一个以患者为导向的残疾和残疾障碍相关研究的首要计划。在过去的十年中，候选人已经建立了一个非常成功的和独立的以病人为导向的研究计划，解决有关流行病学和预防的基本问题， 残疾。K24奖将允许候选人进一步推进老年医学中这一严重和普遍问题的科学知识基础，为他提供受保护的时间来完成本申请中提出的以患者为导向的研究项目。反过来，这个研究计划将为候选人大大扩展的导师计划提供平台，其中包括教学培训，实践研究导师和研究基础设施（数据分析和研究助理支持）。候选人计划在头两年的每一年接受两到三名初级调查员参加该项目。因此，每年接受的候选人人数将有所不同，以实现在任何时候都有5至6名在职受训人员的最终目标。耶鲁大学的环境提供了理想的环境，充满了跨学科的研究和培训计划，跨学科的专业知识和合作，以及资源（例如，方法咨询，生物统计支持，访问研究人群和数据库），以培养候选人，拟议的研究项目和导师计划。总之，候选人在以患者为导向的研究方面的成就，他指导初级研究人员的能力和承诺，以及耶鲁联合收割机的研究和培训优势，为成功实现本提案的具体目标提供了理想的背景。

DESCRIPTION (provided by applicant): The specific aims of this Midcareer Investigator Award in Patient-oriented Research are: (1) to further establish the candidate's independent patient-oriented research program in the epidemiology and prevention of disability among community-living older persons; and (2) to establish a formal mentorship program for junior investigators, across disciplines, who are pursuing patient-oriented aging research related to disability and disabling disorders. This includes functional assessment in general as well as the functional consequences of highly prevalent disease-specific conditions such as arthritis, heart disease, diabetes, stroke, cancer, depression, and dementia. The candidate's ultimate objective is to build a premier program in patient-oriented research related to disability and disabling disorders. During the past ten years, the candidate has established a highly successful and independent patient-oriented research program addressing fundamental issues related to the epidemiology and prevention of disability. A K24 Award will permit the candidate to further advance the scientific knowledge base of this serious and pervasive problem in geriatric medicine by affording him the protected time to complete the patient-oriented research projects proposed in this application. This program of research, in turn, will provide the platform for the candidate's greatly expanded mentorship program, which will include didactic training, hands-on research mentorship, and a research infrastructure (data analytic and research assistant support). The candidate plans to accept two to three junior investigators into the program during each of the first two years. Subsequently, the number of accepted candidates per year will vary to achieve the ultimate goal of having 5 to 6 active trainees at any one time. The Yale environment provides the ideal setting, replete with interdisciplinary research and training programs, interdisciplinary expertise and collaboration, and resources (e.g., methodological consultation, biostatistical support, access to study populations and databases) to foster the candidate, the proposed research projects, and the mentorship program. In summary, the candidate's accomplishments in patient-oriented research, his ability and commitment to mentoring junior investigators, and the research and training strengths of Yale combine to provide an ideal context for successfully carrying out the specific aims of this proposal.