Clinical Research in STDs

描述（由申请人提供）：性传播疾病对社会造成严重影响。每年，美国的性病病例超过1300万例，全世界超过2.5亿例。目前缺乏年轻的临床研究人员，特别是在公共卫生进口巨大的领域，如性病。约翰霍普金斯在性病和公共卫生预防方面有着悠久的临床研究传统，并为指导新的研究人员提供了支持性的环境。 这项建议将借鉴我们过去在指导调查人员方面的成功经验。在最初的赠款期间，PI在约翰霍普金斯建立了一个STD卓越中心，获得了T32培训赠款，以资助STD研究的受训人员，获得了5名博士后CDC STD研究员的资金，指导了32名博士前和博士后研究人员，产生了28份同行评审的出版物，举办了一系列研讨会，并开发了STD方法的入门和高级课程，包括以远程教育形式提供的课程。该方案的一个独特方面是在没有性传播疾病培训能力的其他机构培养调查人员。在此更新申请中，PI建议继续发展指导关系，其中包括：在巴尔的摩STD诊所和约翰霍普金斯艾滋病服务中心的临床经验;流行病学和生物统计学培训，以及演讲和论文写作技能。根据技能水平，学员每周或每两周参加一次会议。所有各级的学员都将制定一个独立的研究项目，并在国家会议上提出报告和出版物。

DESCRIPTION (provided by applicant): Sexually transmitted diseases exact a heavy toll on society. Annually, the number of STD cases exceed over 13 million in the United States and over 250 million cases worldwide. There is a current shortage of young clinical investigators, especially in areas with enormous public health import-such as STDs. Johns Hopkins has had a long tradition of performing clinical research in STDs and public health prevention, and provides a supportive setting for mentoring new investigators. This proposal will build on our past successful experiences in mentoring investigators. During the initial grant period, the PI established an STD Center for Excellence at Johns Hopkins, received a T32 training grant to fund trainees in STD research, received funding for 5 postdoctoral CDC STD fellows, mentored 32 pre and postdoctoral investigators resulting in 28 peer reviewed publications, instituted a seminar series and developed introductory and advanced courses in STD methods, including a course provided in distance education format. A unique aspect of the program is development of investigators at other institutions which do not have STD training capacity. In this renewal application, the PI proposes to continue developing mentoring relationships which will include: clinical experiences in the Baltimore STD clinics and Johns Hopkins AIDS Service; epidemiology and biostatistical training, and presentation and manuscript-writing skills. Mentees are supervised with weekly or biweekly conferences depending on skill level. Mentees at all levels are expected to develop an independent research project resulting in presentation at national meetings and publication.