Penn State: ABSL-3 Facility Construction

描述（由申请人提供）：宾夕法尼亚州立大学提议建造一座新的1,858平方米（20,000平方英尺）的动物生物安全三级（ABSL-3）建筑。急需这一基金来支持在新兴病原体、人畜共患病、媒介传播疾病、宿主病原体界面和疫苗开发方面不断扩大的研究项目。由于目前校园内没有ABSL-3空间，这座建筑将满足安全研究高传染性病原体的巨大空间需求。该建筑将包括微生物学和病毒学实验室、细胞分选能力、动物生物防护套房和昆虫室。19名教员研究人员计划利用这个新设施。此外，宾夕法尼亚州立大学正在传染病和病原体进化领域积极招募6-12名新教员。这座大楼将加强我们的招聘工作，并使我们能够扩大我们在传染病方面的研究。宾夕法尼亚州立大学早就认识到需要一个ABSL-3设施。最初的计划是在2007年制定的，但项目没有启动（因为项目估计几乎是可用预算的三倍）。宾夕法尼亚州立大学承诺拨款800万美元，并要求拨款1500万美元来完成这个估计耗资2300万美元的项目。我们组建了一个具有丰富的ABSL-3经验的项目团队，将在预算内按时完成我们的绿色和可持续建筑，在此过程中为美国创造超过320个就业机会。除了上述新教员外，宾夕法尼亚州立大学还承诺雇用一名ABSL-3设施经理和其他工作人员，并为设施的维护和运营提供持续的预算支持。

DESCRIPTION (provided by applicant): Penn State proposes to build a new 1,858 m2 (20,000 GSF) animal biosafety level three (ABSL-3) building. This facility is critically needed to support expanding research programs in emerging pathogens, zoonoses, vector borne diseases, the host pathogen interface, and vaccine development. As there is currently no ABSL-3 space on campus, this building will fulfill a significant need for space to safely study highly infectious agents. The building will include microbiology and virology laboratories, cell sorting capabilities, animal biocontainment suites, and an insectary. Nineteen faculty researchers have plans to utilize this new facility. In addition, Penn State is actively recruiting 6-12 new faculty members in the area of infectious disease and pathogen evolution. This building will enhance our recruiting efforts, and allow us to broaden our research efforts in infectious disease. Penn State has long recognized the need for an ABSL-3 facility. Initial plans were developed in 2007, but the project was not initiated (as project estimates were nearly triple the available budget). Penn State is committed to allocating $8 million, and requests $15 million to complete the estimated $23 million project. We have assembled a project team with considerable ABSL-3 experience that will complete our green and sustainable building within budget and on time, creating over 320 American jobs in the process. In addition to the new faculty members above, Penn State is committed to hiring an ABSL-3 facility manager and other staff, as well as providing ongoing budgetary support for the maintenance and operation of the facility.