University of Michigan Institute for Social Research Expansion

描述（由申请人提供）：认识到社会，心理和生活方式因素（健康的社会决定因素）在疾病发作，进展和改善中发挥的关键作用，NIH在过去二十年中支持了越来越多的关于健康的社会和行为维度的校外研究。社会研究所（ISR）在健康社会科学研究的这一演变中发挥了重要作用，目前它在NIH支持的研究中投入了近2.5亿美元，从小型临床研究到社区干预，再到对大规模人群样本的长期纵向小组研究。事实上，20年的健康和退休研究（HRS）是拟议的基础设施扩建的主要受益者，是密歇根大学最大的一笔NIH赠款，密歇根大学是美国NIH支持的生物医学研究的领导者之一。在同一时期，与健康有关的社会和行为科学研究的性质几乎发生了一场革命，越来越多地发展了更复杂的理论模型和假设，包括生物测定和生物措施以及遗传物质的使用。分子生物学技术的进步，特别是脑科学的进步，推动了知识的惊人增长，进一步推动了这一演变。ISR在这些发展中再次发挥了重要作用。像HRS这样的研究现在经常收集生物和生物特征测量，ISR的NIH研究的跨学科基础已经发展到包括研究医生，遗传学家，流行病学家和其他与心理学家，社会学家和经济学家合作的健康科学家。这些变化导致了研究科学家的类型和数量的大幅扩张，简单地说，ISR正在迅速耗尽空间。新的空间必须适合这种新型的社会和行为科学研究、存储和检索设施，以及新一代的科学家，他们需要并正在迅速被雇用，以研究健康和疾病的社会决定因素（和相关因素）。本申请要求支持ISR的物理扩展，以包括设计、收集、存储和检索人体数据所需的技术基础设施的适当空间，以及容纳申请中所述ISR不断增长的生物社会和生物行为科学工作人员所需的办公室和会议室空间。密歇根州受到全国经济衰退的打击尤其严重。这笔资金将在短期内提供建筑就业机会，并在长期内提供所需的空间，以容纳我们目前和预计在未来10年内雇用的不断增长的新的科学劳动力。

DESCRIPTION (provided by applicant): In recognition of the critical role that social, psychological, and lifestyle factors (social determinants of health) play in disease onset, progression, and amelioration, the NIH over the last two decades has supported an increasing portfolio of extramural studies on social and behavioral dimensions of health. The Institute for Social Research (ISR) has played a major role in this evolution of social science research on health, and it has at present nearly a quarter of a billion dollars in active NIH supported studies, ranging from small clinical studies, to community interventions, to long-running longitudinal panel studies on large population based samples. In fact, the 20-year Health and Retirement Study (HRS), a major beneficiary of the proposed infrastructure expansion, is the largest single NIH grant at the University of Michigan, a university that ranks among the U.S. leaders in NIH supported bio-medical research. Over this same period, there has been almost a revolution in the nature of health related social and behavioral science research, with the increasing development of more sophisticated theoretical models and hypotheses that include biometric and biological measures and the use of genetic material. This evolution has been furthered by the amazing increase in knowledge propelled by advances in molecular biological technologies, and especially brain sciences. Again the ISR has played a major role in these developments. Studies like the HRS now routinely collect biological and biometric measures, and the interdisciplinary base of ISR's NIH research has evolved to include research physicians, geneticists, epidemiologists, and other health scientists working in concert with psychologists, sociologists, and economists. These changes have resulted in a large expansion of both the type and quantity of research scientists and, simply put, the ISR is fast running out of space. New space must be suited for this new type of social and behavioral science research, storage, and retrieval facilities, as well as for the generation of new scientists that are needed, and are rapidly being hired, to work on this cutting edge of the social determinants (and correlates) of health and diseases. This application requests support to expand physically the ISR to include appropriate spaces for the technical infrastructure needed for the design, collection, and storage and retrieval of human data, as well as the office and meeting room spaces needed to house the growing bio-social and bio-behavioral science workforce at ISR described in the application. The State of Michigan has been particularly hard hit by the national economic downturn. This funding will provide construction employment in the short run, and in the long term the space needed to house the growing new scientific workforce we are currently, and anticipate, hiring over the next 10 years.