FHL Research Symposium: Genomics and the Life Aquatic

描述（由申请人提供）：人类基因组计划打开了大规模基因组测序的闸门，许多不同生物体的基因组正在以前所未有的速度进行测序。生物学家现在面临的挑战是提取编码在这些基因组中的有趣信息，然后可以用来获得生物学家几个世纪以来一直在努力解决的基本问题的新见解。特别是，“比较基因组学”这一新领域已开始对物种的起源、体型的差异、对新环境的适应以及生命本身的起源提供重要的见解。水生环境中生命的多样性为这些研究提供了特别丰富的来源。为了深入了解这些进化过程，需要广泛的专业知识，需要不同背景的科学家之间的相互交流和整合。这可以在一个小型研讨会环境中实现，参与者非常感兴趣，参与和互动。因此，我们召集了一群不同的顶尖科学家参加一个小型研讨会，题为“基因组学和水生生命”，在华盛顿州圣胡安岛的星期五港实验室（FHL）举行。 本次研讨会的目标是：（1）讨论和综合目前的基因组学方法;（2）讨论适应和进化的基础基因组变化的新模式;（3）确定现有工具的原始应用并开发新方法;（4）促进年轻科学家参与进化基因组学这一新兴领域。虽然这次研讨会将重点放在水生生物，出现的主题和教训将适用于生物体和性状的多样性，特别是人类健康和疾病的基因组分析。

DESCRIPTION (provided by applicant): The Human Genome Project opened the floodgates of large-scale genome sequencing, and the genomes of many disparate organisms are being sequenced at a previously unthinkable rate. The challenge now facing biologists is to extract the interesting information encoded in these genomes, which can then be used to gain novel insights into the fundamental problems that biologists have struggled with for centuries. In particular, this new field of "comparative genomics" has begun to provide important insights into the origins of species, divergence of body forms, adaptation to new environments and the origins of life itself. The diversity of life in aquatic environments provides a particularly rich source for these studies. To gain insights into these evolutionary processes, a broad range of expertise is needed, necessitating crosstalk and integration between scientists with diverse backgrounds. This can be achieved in a small symposium setting where participants are highly interested, engaged, and interactive. Therefore, we have assembled a diverse group of leading scientists to participate in a small symposium entitled "Genomics and the Life Aquatic" in a retreat-like setting at the Friday Harbor Laboratory (FHL) on San Juan Island, WA. The goals of this symposium are: (1) to discuss and synthesize current genomic approaches; (2) to discuss emerging patterns of genomic changes that underlie adaptation and evolution; (3) to identify original applications for existing tools and to develop novel approaches; and (4) to promote the participation of young scientists in this emerging field of evolutionary genomics. Although this symposium will focus on the life aquatic, the themes and lessons that emerge will be applicable to genomic analysis of a diversity of organisms and traits, particularly human health and disease.