Transcriptional Regulation During Cell Growth Differentiation and Development

描述（由申请人提供）：部分资金是要求为期五天的FASEB会议“在细胞生长，分化和发展过程中的转录调控”将于2006年8月在萨克顿河，佛蒙特州举行。 转录调控是控制细胞生长、分化、器官发生和癌症的许多信号转导和发育途径的最终和关键终点。 理解调控转录的网络和机制对于理解正常生长和发育是必要的，并且转录失调是许多疾病、发育缺陷和肿瘤转化的基础。 本次会议的目的是汇集生物化学家和分子生物学家研究转录的基本机制，细胞和发育生物学家研究依赖于转录调控的生物过程，以及科学家使用全球方法来了解参与细胞生长，分化和疾病模型转录调控的相互作用基因网络。 这次FASEB会议在这些领域是独一无二的，因为它不是专注于一个单一的主题，而是汇集了科学家使用不同的方法来研究不同系统中的转录调控。 这种跨学科的方法促进了思考问题的新方式，找到了该领域长期存在的问题的解决方案，也许最重要的是，基础科学和生物医学研究的交叉施肥。 会议还将提供生物学中最快速发展的领域之一的最新观点。

DESCRIPTION (provided by applicant): Partial funding is requested for a five day FASEB conference on "Transcriptional Regulation during Cell Growth, Differentiation, and Development" to be held at Saxtons River, Vermont in August 2006. Regulation of transcription is the ultimate and crucial endpoint for many signal transduction and developmental pathways that control cell growth, differentiation, organogenesis, and cancer. Understanding the networks and mechanisms that regulate transcription is necessary to understand normal growth and development, and transcriptional misregulation is the basis for many diseases, developmental defects, and neoplastic transformation. The purpose of this conference is to bring together biochemists and molecular biologists studying fundamental mechanisms of transcription, cell and developmental biologists studying biological processes dependent on transcriptional regulation, and scientists using global approaches to understand networks of interacting genes involved in transcriptional regulation of cell growth, differentiation, and disease models. This FASEB meeting is unique within these fields because rather than focusing on a single topic, it brings together scientists using different approaches to study transcriptional regulation in diverse systems. This interdisciplinary approach fosters new ways of thinking about problems, finding solutions to longstanding questions in the field, and, perhaps most importantly, cross-fertilization of basic science and biomedical research. The conference will also provide an up to date view of one of the most rapidly moving fields in biology.