2006 Microbial Stress Response Gordon Conference

描述（由申请人提供）：本提案要求部分支持将于2006年7月9日至14日在马萨诸塞州南哈德利山霍利奥克学院举行的2006年戈登微生物应激反应研究会议。这次非常成功的会议的2006年会议将强调使用跨学科方法来研究微生物应激反应。已确认的发言者代表了从物理/计算科学和生物科学两方面处理生物医学研究问题的学科。这种跨学科的方法和互动对于实现生物医学研究的下一个突破至关重要。这次会议也因其对应激反应的广泛研究和前沿方法而闻名。因此，它允许新的思想和方法的交叉施肥，以研究这个重要的领域和超越。如会议名称所示，本次会议将包括病原生物与其宿主的关联所引起的应激反应以及生物体在其自然环境中的生存。因此，会议将提高我们对细菌在人类健康和疾病中的作用的理解。此外，今年我们将有一个会议来检查系统生物学/计算方法来解剖应激反应网络，包括单细胞方法。我们还将有几位真核系统的演讲者（包括结构生物学，DMA损伤传感和氧化应激）。会议将重点介绍金属和氧化应激的新进展，以及专业和一般应激反应。此外，我们致力于多元化，我们的演讲者包括女性、未被充分代表的少数民族和新教员。除了每次会议的邀请演讲者外，我们将从提交的摘要中选择额外的演讲者。总之，本次会议将通过整合前沿、结构、分子和计算科学方法来研究微生物系统及其应激反应，在推进微生物研究方面发挥战略性作用。这次会议提供了一个无与伦比的场所，汇集了计算和实验科学家，旨在开发研究压力反应的新方法，从而发现对人类健康和疾病重要的新知识。

DESCRIPTION (provided by applicant): This proposal requests partial support for the 2006 Gordon Research Conference on Microbial Stress Responses to be held July 9-14, 2006 at Mount Holyoke College, South Hadley, MA. The 2006 session of this extraordinarily successful meeting will emphasize the use of cross-disciplinary approaches to study microbial stress responses. The confirmed speakers represent disciplines that approach problems in biomedical research from both the physical/computational sciences and biological sciences. Such cross-disciplinary approaches and interactions are critical to achieving the next breakthroughs in biomedical research. This meeting is also distinguished for its broad examination and cutting edge approaches to the study of stress responses. As such, it allows the cross fertilization of new ideas and approaches to the study of this important field and beyond. As indicated by the session titles, this meeting will include stress responses of pathogenic organisms induced by association with their hosts as well as the survival of organisms in their natural environment. Thus the sessions will improve our understanding of the role of bacteria in human health and disease. In addition, this year we will have a session to examine systems biology/computational approaches to dissecting stress responses networks, including single cell approaches. We will also have several speakers working on eukaryotic systems (including structural biology, DMA damage sensing and oxidative stress). The meeting will highlight new developments in metal and oxidative stress, as well as specialized and general stress responses. In addition, we are committed to diversity and our speakers include women, underrepresented minorities and new faculty. Besides the invited speakers in each session, we will choose additional speakers from submitted abstracts. In summary, this meeting will play a strategic role in advancing microbial research by integrating cutting edge, structural, molecular, and computational science approaches to the study of microbial systems and their stress responses. This meeting provides an unparalleled venue to bring together computational and experimental scientists with the aim of developing new approaches to study stress responses, thereby uncovering new knowledge important to human health and disease.