Oklahoma IDeA Network of Biomedical Research Excellence

描述(由申请者提供)：俄克拉荷马州的IDEA生物医学研究卓越网络(INBRE)将通过支持有前途的新教师、招收学生进入生物医学研究事业以及维持重要的核心设施来建设州开展生物医学研究的能力。该网络是多样化的，由两个主要任务是生物医学研究、教育和病人护理的主要机构和12个合作机构组成。该网络包括俄克拉何马州唯一的历史上唯一的黑人学院和大学，一个主要是本科生的机构，在全国所有大学中美洲原住民人数最多的机构，俄克拉何马州唯一的部落学院，以及其他几个机构，拥有大量来自代表不足的群体的学生。俄克拉何马州INBRE的科学主题是多学科的，目标是微生物学和免疫学、癌症和神经科学领域。这一主题聚焦与两家领先的生物医学研究密集型机构的战略研究计划紧密相连。INBRE将支持主要来自本科生机构的6名研究人员和主要机构的4名研究人员在这些学科方面的研究。通过INBRE提供研究支持的目标将是增加这些研究人员制定独立研究计划的机会。每个参与的研究人员将在INBRE赠款开始后18个月内开发新的NIH赠款申请，以支持他们的研究项目。对学生的支持将通过暑期实习、参与教师研究项目以及注册生物信息学和基因组学新的教育项目来提供。学生将在主要机构和自己的校园参加研究活动。INBRE将支持的主要核心设施将集中在功能基因组学上。一个致力于支持功能基因组学研究的生物信息学设施综合网络也将通过INBRE得到支持。INBRE将支持开发一个新的核心设施，其核心将是专门用于动物研究的功能性磁共振成像仪(MRI)。所有参与INBRE的研究人员都可以使用核磁共振成像，并将支持全州范围内的癌症和神经科学研究。总体而言，INBRE对教师研究、学生和核心设施的支持将是俄克拉荷马州努力在生物医学研究方面具有全国竞争力的重要一步。

DESCRIPTION (provided by applicant): Oklahoma's IDeA Network for Biomedical Research Excellence (INBRE) will build State capacity to carry out biomedical research by supporting promising new faculty, recruiting students into biomedical research careers, and sustaining vital core facilities. The Network is diverse, comprising two lead institutions whose primary missions are biomedical research, education and patient care and twelve collaborating institutions. The Network includes Oklahoma's only Historically Black College and University, a primarily undergraduate institution with the highest number of Native Americans of any college in the nation, Oklahoma's only tribal college, and several other institutions with large numbers of students from underrepresented groups. The scientific themes of Oklahoma's INBRE are multi-disciplinary, targeting the fields of Microbiology & Immunology, Cancer, and Neuroscience. This thematic focus is closely linked with the strategic research plans of the two lead biomedical research-intensive institutions. INBRE will support research in these disciplines by six investigators from primarily undergraduate institutions and four from the lead institutions. The goal of research support through INBRE will be enhancing the opportunity for these investigators to develop independent research programs. Each participating investigator will be expected to develop new NIH grant applications to support their research projects within 18 months of the commencement of the INBRE grant. Support for students will be provided by summer internships, participation in the faculty research projects and enrollment in new educational programs in bioinformatics and genomics. Students will participate in research activities at both the lead institutions and their own campuses. The primary core facilities to be supported by INBRE will be focused on functional genomics. An integrated network of bioinformatics facilities dedicated to supporting research in functional genomics will also be supported through INBRE. INBRE will support the development of a new core facility whose centerpiece will be a functional magnetic resonance imager (MRI) devoted exclusively to animal research. The MRI is available to all participating INBRE investigators and will support statewide research in cancer and neuroscience. Collectively, INBRE support for faculty research, students and core facilities will be a major step in Oklahoma's efforts to become nationally competitive in biomedical research.