Eighth & Ninth International Symposia on Neurobiology & Neuroendocrinology Aging

第八届和第九届国际神经生物学和神经内分泌学衰老研讨会将于2006年7月23日至28日和2008年7月在奥地利布雷根茨举行。这些会议的目的是汇集一组最近在衰老机制研究方面取得重大进展的研究人员，特别强调CNS衰老，神经保护，神经退行性疾病的检测和治疗。2006年将涉及的具体主题包括线粒体和染色体DNA损伤的作用、自噬、胰岛素抵抗、晚期糖基化产物、应激抵抗、瘦素、伴侣蛋白和朊病毒、TGF β、IGF-1亚型和雌激素的神经发生和神经保护作用，以及 早期发现和治疗阿尔茨海默病的新方法。此外，还对C. elegans和衰老在一个非常短命的脊椎动物物种将提出。我们故意包括广泛的主题，并聚集了一群通常不会参加同一次会议的科学家。会议的形式是仿照戈登研究会议，并鼓励正式和非正式的讨论所提出的材料。会议记录将在研讨会后约6个月内作为《实验老年学》特刊出版。强烈鼓励初级研究人员，包括研究生和博士后研究员的参与，该提案寻求资金，为正在接受培训或担任初级教师职位并计划在海报会议上展示其研究结果的美国参与者提供津贴。我们还在寻求对应邀从美国来的发言者的费用提供部分支助。

DESCRIPTION (provided by applicant): The Eighth and Ninth International Symposia on Neurobiology & Neuroendocrinology Aging will be held in Bregenz, Austria July 23-28, 2006 and in July 2008. The purpose of these meetings is to bring together a group of investigators who made recent significant advances in the study of mechanisms of aging, with particular emphasis on CNS aging, neuroprotection, detection and treatment of neurodegenerative disease. Specific topics to be covered in 2006 will include the role of damage of mitochondrial and chromosomal DNA, autophagy, insulin resistance, advanced glycation products, stress resistance, leptin, chaperones, and prions, neurogenesis and neuroprotective effects of TGF beta, IGF-1 isoforms, and estrogens, as well as novel approaches to early detection and treatment of Alzheimer's disease. In addition, new data on genetics of aging in C. elegans and on aging in an exceptionally short-lived vertebrate species will be presented. We purposely include a wide range of topics and assemble a group of scientists that may not normally attend the same meeting. The format of the meeting is modeled after Gordon Research Conferences and encourages formal and informal discussions of the material presented. Proceedings will be published as a special issue of Experimental Gerontology within approximately 6 months after the Symposium. Participation of junior investigators, including graduate students and post-doctoral fellows is strongly encouraged and this proposal seeks funds for providing stipends to those US participants who are in training or are in junior faculty positions and who are planning to present their findings in the poster session. We are also seeking partial support for the expenses of invited speakers from the United States.