Clinical Core

临床核心A的主要目的是为anca相关的小血管炎（SW）患者提供途径，以便获得生物样本和临床信息，用于本项目的三个拟议项目。能够接触到这些患者群体和处于不同疾病阶段的患者，对于成功完成这些项目至关重要。在这一患者群体中，特别感兴趣的临床阶段包括：缓解、治疗缓解、治疗抵抗、复发和终末期肾脏疾病。该中心还将负责处理和储存生物样品，以及管理关于同意表格、标本标签和储存地点以及疾病阶段和结果的临床评估的数据库。核心还将提供研究设计和统计专业知识，以出版和呈现摘要和

The primary purpose of Clinical Core A is to provide access to patients with ANCA-associated small vessel vasculitis (SW) in order to obtain biological samples in conjunction with clinical information for the use in three of the proposed projects of this program project. Access to this patient population and to patients at different disease stages is critical for the successful completion of these projects. Clinical stages of particular interest in this patient population include: remission, remission on therapy, treatment resistance, relapse and end stage renal disease. The Core will also be responsible for processing and storing biologic samples, as well as managing the database with respect to consent forms, labeling and storage locations of specimens, and clinical assessment of disease stages and outcomes. The Core will also provide the study design and statistical expertise needed to publish and present abstracts and manuscripts. The faculty and staff who comprise the Core have a long term commitment to research in this arena and have well documented track record of publishing abstracts and manuscripts with the principal and co-investigators, with a particular focus in the area of vasculitis.