Improving Metabolic Control in Diabetic Young Children

描述（由申请人提供）：尽管对T1 DM幼儿进行早期干预可能有助于预防代谢控制方面的后期问题，但一些潜在的研究障碍限制了此类干预措施的发展。为了评估对幼儿及其家庭进行早期干预的可行性，我们建议对新诊断为T1 DM的幼儿（7-11岁）进行行为预防干预的探索性试点研究。该干预措施源于Seligman及其同事的儿科预防工作，旨在应用积极心理学原则来增强糖尿病管理中的乐观主义，自我效能和亲子合作，以改善生活质量，坚持和代谢控制。这项探索性研究将使我们能够评估在诊断时对幼儿及其照顾者进行干预的可行性，并估计干预效果大小，为随机对照临床试验做准备。

DESCRIPTION (provided by applicant): Although early intervention with young children with T1 DM may help forestall later problems in metabolic control, a number of potential barriers to research have constrained the development of such interventions. To assess the feasibility of intervening early with young children and their families, we propose to conduct an exploratory pilot study of a behavioral prevention intervention for young children (ages 7-11) newly diagnosed with T1DM. The intervention, derived from the pediatric prevention work of Seligman and his colleagues, seeks to apply positive psychology principles to enhance optimism, self-efficacy, and parent- child collaboration in diabetes management, in order to improve quality of life, adherence, and metabolic control. This exploratory study will allow us to evaluate the feasibility of intervening with young children and their caretakers at the point of diagnosis and to estimate intervention effect sizes in preparation for a randomized controlled clinical trial.