Fathoming sleep depth: a novel approach to the understanding and assessing of sleep-state misperception in insomnia

我们都需要睡眠，但并不是每个人都睡得好。尽管失眠会带来深远的影响，但有些人睡得好而有些人睡得不好的原因在很大程度上是未知的。我们提出一些人报告睡眠不佳的一个原因是由于大脑在睡眠期间异常地监控内部和外部世界。通过专注于了解失眠的机制，我希望在设计更有效的个性化治疗方法方面迈出关键一步。

We all need to sleep and, yet, not everyone sleeps well. The reasons why some sleep well and others do not is largely unknown, despite the far-reaching consequences of insomnia. We propose one reason some people report poor sleep is due to the brain abnormally monitoring the internal and external world during sleep. By focusing on understanding the mechanisms underlying insomnia, I hope to take a crucial step in devising more efficient individualised therapeutic approaches.