Implications of OAE Cochlear Source Contribution

目前的观点认为，两个耳蜗源导致了畸变产物耳声发射（dpoae），一个失真源和一个反射源。相比之下，低刺激频率oae （sfoae）被认为是由反射源贡献主导的。有人提出，如果减少或消除反射源的贡献，dpoae将更准确地预测行为阈值和识别听觉状态，尽管这一假设尚未得到验证。本研究的主要目的是确定耳蜗源对声发射测试成绩的影响。提出了四个具体目标。1)确定降低反射源对dpoae贡献的最有效抑制音。2)将在正常和受损人耳中评估传统（双源）dpoae、失真源dpoae（反射源抑制）和sfoae预测行为阈值的准确性。3)临床决策理论将用于评估双源（传统dpoae）和单源（失真源dpoae和sfoae）听觉状态二分类决策的准确性。4)精细结构（被认为是由dpoae的畸变源和反射源能量的复杂总和产生的）在预测和诊断误差中的作用将被评估。

Current thinking suggests that two cochlear sources contribute to distortion product otoacoustic emissions (DPOAEs), a distortion source and a reflection source. In contrast, low-level stimulus frequency OAEs (SFOAEs) are believed to be dominated by reflection-source contributions. It has been proposed that DPOAEs would more accurately predict behavioral threshold and identify auditory status if the reflection-source contribution is reduced or eliminated, although this hypothesis has not been tested. The broad objective of the proposed study is to determine the influence of cochlear-source contribution on OAE test performance. Four specific aims are posed. 1) The most effective suppressor tone for reducing the reflection-source contribution to DPOAEs will be determined. 2) Accuracy in predicting behavioral thresholds from traditional (two-source) DPOAEs, distortion-source DPOAEs (reflection source suppressed), and SFOAEs, will be evaluated in normal and impaired human ears. 3) Clinical decision theory will be used to evaluate the accuracy with which dichotomous decisions regarding auditory status are made with two-source (traditional DPOAEs) and single-source OAEs (distortion-source DPOAEs and SFOAEs). 4) The role of fine structure (thought to arise from the complex summation of distortion- and reflection-source energy for DPOAEs) in prediction and diagnostic errors will be evaluated.