Proactive Cessation Intervention with Biomarker Feedback

描述(由申请人提供)：迫切需要经验性的、以社区为基础的、激励性戒烟干预措施。理论和经验证据都表明，使用吸烟生物标志物来教育人们与吸烟相关的个人健康风险和健康并发症可能是增强戒烟动机的有效策略，特别是在吸烟者被教育了解他们的肺功能和一氧化碳暴露的情况下。当这些信息与最佳实践治疗相结合时，它也可能是促进禁欲的一种有效方式。 目前的研究将测试以社区为基础的干预措施的有效性，该干预措施结合了个性化的生物标记物反馈，以建立戒烟动机，并获得被证明有效的、以行动为导向的戒烟治疗。参与者(N=650)将在社区中招募，并随机分为治疗组或对照组。治疗参与者将接受基于生物的激励治疗，包括对他们的一氧化碳(CO)暴露、肺功能和自我报告的吸烟相关症状的反馈。控制组的参与者将收到通用的烟草风险信息。所有参与者都将免费获得全面的戒烟治疗，如果他们决定戒烟，可以获得这些治疗。主要目的是确定，与普通干预相比，基于生物的治疗是否增强了吸烟者戒烟的动机，增加了戒烟治疗的利用，还是增加了戒烟率。这项研究还将检查这些影响的潜在调解人和调节者，并测试与干预相关的负面情绪困扰。拟议的干预措施旨在适用于所有自愿的参与者，并将比标准的戒烟治疗覆盖范围更广。如果有效，这种治疗策略可能会作为一种公共卫生干预措施具有广泛的潜力。

DESCRIPTION (provided by applicant): Empirically-validated, community-based, motivational smoking cessation interventions are critically needed. Both theoretical and empirical evidence suggests that using smoking biomarkers to educate people about their personal health risks and health complications associated with smoking can be an effective strategy for enhancing motivation to quit, especially when smokers are educated about their pulmonary functioning and CO exposure. When this information is coupled with best-practices treatment, it may also be an effective way to promote abstinence. The current study will test the effectiveness of a community-based intervention that combines personalized biomarker feedback to build motivation for quitting with access to proven-effective, action-oriented cessation treatment. Participants (N = 650) will be recruited in the community and randomized to treatment or control. Treatment participants will receive biologically-based motivational treatment that includes feedback on their carbon monoxide (CO) exposure, pulmonary functioning, and self-reported smoking-related symptomology. Participants in the control group will receive generic tobacco risk information. All participants will be given free access to comprehensive cessation treatment that can be accessed if and when they decide to quit. The primary aims are to determine if, compared to generic intervention, the biologically-based treatment enhances smokers' motivation to quit, increases utilization of cessation treatment, or increases abstinence rates. The study will also examine potential mediators and moderators of these effects and will test for negative emotional distress associated with the intervention. The proposed intervention is designed to be applicable for all willing participants and will have greater reach than standard cessation treatment. If effective, this treatment strategy could have broad potential as a public health intervention.