South Texas Pediatric Minority Based CCOP

描述（由申请人提供）：南德克萨斯州儿童少数族裔社区临床肿瘤学项目（STP-MB-CCOP）的长期目标是降低居住在服务区的墨西哥裔美国人（MA；此处与西班牙裔同义）儿童和青少年的癌症发病率、发病率和死亡率。STP-MB-CCOP的四个具体目标是：1)为服务于南德克萨斯州地理区域的儿科肿瘤学提供者提供全面、集成的数据管理服务；2)为儿科肿瘤科医生、数据管理人员和支持人员提供到医疗服务区域外展诊所的差旅支持；3)为服务区的墨西哥裔美国人提供具有文化敏感性的集中西班牙语翻译系统；4)发展与服务地区墨西哥裔美国人相关的当地癌症控制试点计划。该研究计划涉及圣安东尼奥临床研究办公室的运作，该办公室负责协调各组成机构的数据管理活动，包括主要数据收集和提交、IRB批准、西班牙语翻译、研究基地审计和样本收集。它将使用信息学数据交换和获取系统（IDEAS），这是一个基于网络的系统，所有STP-MB-CCOP中心都可以访问该系统，无论其位置如何。将在边境县提供各级外联活动（教育、儿科肿瘤学家的数据管理支持和外联诊所），使患癌症的儿童和青少年有机会参加临床试验。同意表格和教育材料的西班牙语集中翻译将确保所有患者和家属以他们自己的语言获得信息，从而对遵守治疗产生积极影响。STP-MB-CCOP正试图通过发展与墨西哥裔美国人相关的地方癌症控制倡议，并扩展到其他COG CCOP机构，来补救儿童癌症控制和预防试验的缺乏。该计划有一个持续的评估计划，包括机构pi与其cra之间的每周会议，行政执行委员会的月度会议和所有STP-MB-CCOP成员的季度会议，以审查联盟的活动。

DESCRIPTION (provided by applicant): The long-term goal of the South Texas Pediatric Minority-Based Community Clinical Oncology Program (STP-MB-CCOP) is to reduce the incidence, morbidity and mortality of cancer among Mexican-American (MA; herein used synonymously with Hispanic) children and adolescents residing in the service area. The four specific aims of the STP-MB-CCOP are: 1) Provide comprehensive, integrated data management services accessible to pediatric oncology providers serving the geographic region known as South Texas; 2) Provide travel support for pediatric oncologists, data management and support personnel to outreach clinics within the medically under served areas; 3) Provide a centralized Spanish translation system culturally sensitive to the Mexican-American population in the service area; and 4) Develop local cancer control pilot initiatives relevant to the Mexican-American population in the service area. The research plan involves the operation of a Clinical Research Office in San Antonio that coordinates the data management activities of the component institutions, including primary data collection and submission, IRB approval, Spanish translation, research base audits and sample collection. It will use the Informatics Data Exchange and Acquisition System (IDEAS) a Web based system that can be accessed by all STP-MB-CCOP centers regardless of their location. Outreach activities at all level (education, data management support of resident pediatric oncologist and outreach clinics) will be provided in border counties to allow children and adolescents with cancer to have access to clinical trials. Centralized Spanish translation of consent forms and educational materials will assure that all patients and family receives information in their own language with a resulting positive impact on compliance with treatment. STP-MB-CCOP is attempting to remedy the paucity of pediatric cancer control and preventive trials by developing local cancer control initiatives pertinent to the Mexican-American population and expandable to other COG CCOP institutions. The program has an ongoing evaluation program involving weekly meetings between institution PIs and their CRAs, monthly meeting of the Administrative Executive Committee and quarterly meeting involving all STP-MB-CCOP members to review the consortium activities.