RAND COORDINATING CENTER: SEXUAL DIFFUSION OF HIV STUDY

描述（由申请人提供）： 在这项提案中，我们提出了我们的概念，协调中心的艾滋病毒合作协议计划（SATH-CAP），以支持多学科的研究，旨在更好地了解艾滋病毒的性传播内和跨吸毒人群亚群和非吸毒人群。对于这一具有挑战性的工作，我们坚信其重要性;在相关领域拥有丰富的实质性经验;通过建立共识的过程管理大规模，多地点研究的专业知识;在制定和开展这一主题的研究方面拥有丰富的经验;高超的数据收集和数据管理能力;以及作为研究人员的经验。我们还带来了承担工作的强烈愿望和完成工作的意愿。为此，我们提出了以下具体目标：具体目标1：与研究中心和NIDA合作改进方法和设计;具体目标2：协助指导委员会开发和实施SATH-CAP合作多中心项目组件（即，具体目标3：协调SATH-CAP指导委员会、小组委员会和工作组会议的后勤职能，包括制作和分发委员会议程、背景材料和会议记录;具体目标4：开发和维护SATH-CAP网站，以促进传播易于访问的项目管理工具（例如，进度报告表等）;具体目标五：协助研究中心进行数据质量控制检查，包括数据收集的现场培训，并协助数据管理和分析，包括实施多中心数据管理系统，以促进多中心协作工作;具体目标6：促进跨中心数据可比性，作为本合作研究中收集的数据的存储库，并准备公共使用的数据集;具体目标7：根据指导委员会待制定的程序，协助编写出版物。

DESCRIPTION (provided by applicant): In this proposal, we present our concept of a Coordinating Center for the Sexual Acquisition and Transmission of HIV Cooperative Agreement Program (SATH-CAP) to support multi-disciplinary research that seeks to better understand the sexual transmission of HIV within and across drug-using population subgroups and to non-drug using populations. To this challenging effort, we bring a strong belief in its importance; rich substantive experience in the relevant areas; expertise in managing large scale, multi-site research studies by a process of consensus building; extensive experience in formulating and carrying out research on this topic; superb data collection and data management capabilities; and experience as researchers with being "coordinated". We also bring a strong desire to take on the work and a willingness to see it through to completion. To this end, we propose the following specific aims: Specific Aim 1: Collaborate with Research Centers and NIDA in the refinement of methods and designs; Specific Aim 2: Assist the Steering Committee in developing and implementing the SATH-CAP cooperative multi-center project component (i.e., the HIV behavioral epidemiology of drug use and sexual risk behaviors); Specific Aim 3: Coordinate logistical functions of meetings of the SATH-CAP Steering Committee, subcommittees, and workgroups, including production and distribution of committee agendas, background materials, and minutes; Specific Aim 4: Develop and maintain a SATH-CAP website to facilitate dissemination of easily accessible project management tools (e.g., progress report forms etc.); Specific Aim 5: Assist Research Centers with data quality control checks, including on-site training for data collection, and assist in data management and analysis, including implementing multi-Center data management systems to facilitate multi-Center collaborative work; Specific Aim 6: Facilitate cross-center data comparability, serve as a repository for data collected under this cooperative study, and prepare public use data sets; Specific Aim 7: Assist in development of publications, in accordance with Steering Committee procedures to be developed.