Emerging Infections Program

本提案的长期目标是检测、调查、控制和预防新出现的 传染病这些将通过一个新出现的感染计划来解决， 位于俄勒冈州的州公共卫生管理局，将1）管理积极的公共卫生疾病 监测;2）开展应用公共卫生流行病学和实验室活动; 3）实施和 评估试点预防和干预项目。活动将与其他组织合作进行 州卫生部门和联邦疾病控制和预防中心。 更具体地说，将对细菌病原体的侵入性感染进行主动监测， 包括A和B组链球菌、肺炎链球菌、流感嗜血杆菌和奈瑟氏球菌 脑膜炎和耐甲氧西林金黄色葡萄球菌;肠道和食源性感染 由各种细菌、病毒和原生动物引起;用于病毒性肝炎;用于呼吸道疾病，特别是 医护人员肺炎和流感导致儿童住院;不明原因死亡 似乎是传染性的;和克雅氏病。主动监控将包括 确定疾病高危人口群体和疾病发病率趋势。 该计划将进行流行病学研究，以确定所列疾病的可改变的风险因素 并评估疫苗计划和其他控制措施的有效性。将扩大 公共卫生部门有能力调查疫情，以确定各种病原体的传播途径。 它将扩大公共卫生实验室的鉴定和分子流行病学分析能力， 细菌和病毒病原体。

The long-term objectives of thisproposal are to detect, investigate, control,and prevent emerging infectiousdiseases. These will be accomplishedthroughan Emerging Infections Program createdwithin the state public-health administrationin Oregon, which will 1) conductactive, public-healthdisease surveillance;2) conductapplied public-health epidemiologicand laboratoryactivities;and 3) implement and evaluate pilotprevention and intervention projects. Activitieswill be conductedin collaborationwith other state health departments and the federal Centers for Disease Controland Prevention. More specifically, active surveillancewill be conductedfor invasive infectionby bacterialpathogens, includinggroups A and B streptococci,Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis,and for methicillin-resistantStaphylococcusaureus; for entericand foodborne infections caused by various bacteria, viruses, and protozoa;for viral hepatitis;for respiratory illnesses,especially pneumonia in healthcare workers and influenza causing hospitalizationof children; for unexplaineddeaths that appear to be infectious;and for Creutzfeldt-Jakob disease. Active surveillancewill include the identificationof demographic groupsat high riskfor disease and trends in disease incidence. This program will conduct epidemiologic research to determine modifiable risk factors for diseases listed above and to evaluate the effectiveness of vaccine programs and other controlmeasures. It will expand public-healthcapacityfor investigationof outbreaksto identify means of transmissionof variouspathogens. It will expand public-healthlaboratory capacity for the identificationand molecular epidemiologicanalysis of bacterialand viral pathogens.