Prostate cancer in Blacks: Role of poverty and diet

求职者的长期职业目标是成为癌症预防和控制领域的一名独立调查员，重点研究癌症发病率和死亡率方面的种族和民族差异。少数群体承受着不平等的癌症负担，候选人建议开发独特的创新方法来帮助理解这些差异。K07将在两个领域提供新的和增强的知识和技能，这两个领域对候选人未来旨在帮助减少癌症健康差距的研究工作至关重要：1)空间流行病学，包括地理信息系统的使用；2)癌症预防和控制，包括健康行为(特别是关于饮食和体力活动的行为)。 拟议的培训计划包括1)课程工作；2)赞助商和合作者的定期指导；3)参加研讨会和国家会议；4)专家辅导；以及5)指导研究。K07的教学经验将被应用于一个有指导的研究项目。 该项目的具体目标：1)开发一个绘制美国东南部前列腺癌发病率地图的地理信息系统；2)开发空间回归模型，旨在解释贫困、收入、城乡居民和种族与前列腺癌发病率地理模式的可能联系；3)在弗吉尼亚州选定的农村和城市地点对非裔美国人和白人的饮食脂肪摄入量进行电话调查；以及4)调查这些地区的饮食脂肪摄入量与前列腺癌发病率之间是否存在任何相关性。K07项目的结果将被用来帮助在非裔美国人社区开发文化上适当的干预措施，以减少饮食脂肪摄入量和增加体力活动。

DESCRIPTION (provided by applicant): The Candidate's long-term career goal is to become an independent investigator in cancer prevention and control, with a focus on studying racial and ethnic disparities in cancer morbidity and mortality. Minority populations bear an unequal cancer burden, and the Candidate proposes to develop unique and innovative methodologies to help understand these disparities. The K07 will provide for the development of new and enhanced knowledge and skills in two areas essential to the Candidate's future research efforts aimed at helping to reduce cancer health disparities: 1) spatial epidemiology, including use of geographic information systems; and, 2) cancer prevention and control, including health behavior (especially regarding diet and physical activity). The proposed training plan includes 1) course work; 2) regular mentoring from Sponsors and Collaborators; 3) participation in seminars and national conferences; 4) tutorials by experts; and, 5) mentored research. K07 didactic experiences will be applied in a mentored research project. Specific Aims of Project: 1) develop a geographic information system that maps prostate cancer incidence in the southeastern United States; 2) develop spatial regression models aimed at explaining the possible association of poverty, income, urban/rural residence, and race to the geographic patterning of prostate cancer incidence; 3) conduct a telephone survey of dietary fat intake among African Americans and whites in selected rural and urban sites in Virginia; and 4) investigate whether any correlation exists between dietary fat intake in these areas and the incidence of prostate cancer. K07 project findings will be used to help develop culturally appropriate interventions in African-American communities to decrease dietary fat intake and increase physical activity.