CORE--Proteomics

这一新的共享资源将蛋白质组学研究技术应用于俄亥俄州立大学的癌症问题。虽然蛋白质组学在很大程度上与通过质谱学鉴定蛋白质有关，但信息学工具和高通量分析仪器的协同作用揭示了生物标记物发现和系统生物学的新机遇，这两者都将在研究所未来的癌症研究中发挥关键作用。俄勒冈健康与科学大学(OHSU)最近投资190万美元开发了一个校园范围的蛋白质组学单元，该单元将作为OHSU癌症研究所的蛋白质组学共享资源(PSR)。我们在这里申请的资金将用于主任和技术人员的那部分工资支持，我们预计将用于支持研究所成员的癌症项目。通过CCSG实现薪金稳定，还将允许共享资源开发技术，以解决成员的独特关切。

This new shared resource brings proteomic research techniques to bear on the cancer problem at OHSU. While proteomics has been largely associated with protein identification by mass spectrometry, the synergy of informatics tools and high-throughput analytical instrumentation has revealed new opportunities in biomarker discovery and systems biology, both of which will play a key role in future cancer research in the Institute. Oregon Health and Science University (OHSU) has recently invested $1.9m in developing a campus wide proteomics unit, a unit that will serve as the Proteomics Shared Resource (PSR) of the OHSU Cancer Institute. Funds we request here will contribute to that fraction of salary support of the director and technical staff that we project will be applied to support of cancer projects of Institute members. Salary stabilization through CCSG will also permit the shared resource to develop technologies that address unique concerns of the members.