Improved design of effective anti-cancer therapies via multiscale modelling and simulations

这个项目的目的是阐明肿瘤微环境特征与血液和药物在血管内传递的疗效之间的相互作用，通过适当的基于外部（电磁场）应用的抗癌治疗。学生将获得通过均质化技术获得的新的数学模型，以在组织尺度上描述手头的生物物理系统，同时保留有关肿瘤微观结构的信息。模型的预测将支持在剂量和计划方面的治疗优化。

The aim of this project is to elucidate the interplay between the tumour microenvironment features and the efficacy of blood and drug delivered intravascularly through suitable anti-cancer therapies based on the application of an external (electro-magnetic) field. The student will obtain new mathematical models obtained via homogenisation techniques to describe the biophysical system at hand at a tissue scale level whilst retaining information concerning the tumour microstructure. Model's predictions will support the optimisation of therapy in terms of dosage and scheduling.