Systematic Review: Measures of Sexual Quality of Life for Female Cancer Survivors

描述(由申请人提供)：女性一生中患癌症的几率为1/3。随着存活率的持续上升，越来越多的女性患有癌症。作为回应，临床研究人员将重点放在癌症幸存者的生活质量问题上，例如性生活质量(SQOL)。性行为和亲密关系已被证明在长期生存中扮演着重要角色。然而，越来越多的人担心，SQOL的结构没有充分衡量女性癌症幸存者的结构，包括女性的性反应、生育能力和更年期状态。拟议的项目旨在解决有关使用系统审查技术对女性癌症幸存者的SQOL进行概念化和衡量的关键问题。具体目标是：(1)审查女性SQOL的领域如何随癌症部位、生存阶段、生命阶段和伴侣/配偶的存在而变化；(2)评估关于女性SQOL的研究的质量；(3)描述如何通过审查和确定现有自我报告评估工具中的项目差距来衡量女性癌症幸存者的SQOL；(4)确定研究人员和医生需要了解的关于女性性生活质量的特定癌症和特定性别的关切。运用系统文献回顾的原则，对已发表和未发表的文献进行全面检索。SQOL的广义定义包括性功能和功能障碍、性满足和性健康。样本中每个符合条件的研究将根据一些特征进行编码，例如研究的背景、参与者、方法和研究质量。将严格制定编码程序，以保持有效性和可靠性。我们还将系统地分析大约75个关于项目、分量表和量表水平的评估工具，以记录项目差距，即内容上的重大疏忽。我们的分析将包括但超越传统的信度和效度心理测量学评估。使用我们开发和试验的系统编码系统，我们将对项目内容进行编码，以评估如何解决SQOL领域的问题。这些发现将清楚地总结可用于评估女性癌症幸存者的SQOL的措施和项目的优点和缺点。

DESCRIPTION (provided by applicant): There is a 1 in 3 chance that a woman will develop cancer in her lifetime. As survival rates continue to rise, growing numbers of women are living with cancer. In response, clinical researchers have focused on quality of life issues for cancer survivors, such as sexual quality of life (SQoL). Sexuality and intimacy have been shown to play important roles in long-term survivorship. However, there is growing concern that the construct of SQoL has not been adequately measured for female cancer survivors, including female sexual response, fertility, and menopausal status. The proposed project aims to address key questions regarding the conceptualization and measurement of SQoL for female cancer survivors using systematic review techniques. The specific aims are: (1) To review how the domain of female SQoL varies by cancer site, stage of survivorship, life stage, and the presence of a partner/spouse; (2) To assess the quality of the research on female SQoL; (3) To describe how SQoL has been measured for female cancer survivors by reviewing and identifying item gaps in existing self-report assessment tools; (4) To identify cancer-specific and gender-specific concerns that researchers and physicians need to be informed about concerning women's sexual quality of life. Using the principles of systematic literature review, we will undertake a thorough search of the published and unpublished literature. SQoL is broadly defined to include sexual function and dysfunction, sexual satisfaction, and sexual health. Each eligible study in the sample will be coded with respect to a number of features, such as the setting of the study, participants, methodology, and study quality. Coding procedures will be rigorously developed to maintain validity and reliability. We will also systematically analyze approximately 75 assessment tools on the item, subscale, and scale levels to document item gaps, i.e., a significant oversight in content. Our analysis will include, but go beyond, traditional psychometric assessments of reliability and validity. Using a systematic coding system that we have developed and piloted, we will code item content in order to evaluate how the domain of SQoL has been addressed. The findings will provide a clear summary of the strengths and weaknesses of available measures and items used to assess SQoL among female cancer survivors.