Sexual antagonism and the consequences of sex-specific selection

男性和女性从本质上相同的基因组中产生，但选择的方式却截然不同。这使得基因库在女性化和男性化选择中交替发生，从而促进了性对抗（SA）进化。性染色体被预测在SA进化中扮演重要角色，因为性连锁允许性别特异性基因表达，但是关于性连锁基因作用的数据仅限于果蝇，一种雄性异配子（XY）模型。本项目将利用实验进化和雌性化内共生沃尔巴克氏体通过雌性化选择来强制雄性基因组，确定在蝴蝶Eurema hecabe（雌性ZW异种配子）中SA选择的后果。

Males and females arise from essentially the same genome yet are selected in vastly different ways. This exposes gene pools to alternate episodes of feminising- and masculinising-selection, thereby promoting Sexually Antagonistic (SA) evolution. Sex chromosomes are predicted to play an important role in SA evolution because sex-linkage allows for gender-specific gene expression, but data on the role of sex-linked genes are limited to Drosophila, a male heterogametic (XY) model. This project will determine the consequences of SA selection in the butterfly Eurema hecabe (a female ZW heterogamete) using experimental evolution and the feminising endosymbiont Wolbachia to force male genomes through bouts of feminising selection.