Event Recordings of High Risk Infants on Apnea Monitors

描述（由申请人提供）：该项目的目的是继续对协同家庭婴儿监测评估（CHIME）研究进行具体分析，继续进行全国婴儿睡眠姿势（NISP）研究，并作为CHIME和NISP的公共使用数据集的资源，这些数据集是在上一个拨款奖励期间开发的。CHIME研究在五所大学的临床中心招募了近1100名婴儿。CHIME数据集包括来自900,000小时（300GB）家庭监测记录的原始和分析的生理波形；700张过夜多导睡眠图；21,000例心肺事件超过记录阈值；超过常规警报阈值的6000个事件；超过极限阈值的事件有600起。特别地，CHIME数据的拟议分析将评估预测极端心肺事件的因素和生理过程，包括早期前因、发育模式、发病和恢复的直接特征。NISP研究开始于1992年，是对48个相邻州的8个月以下婴儿夜间看护人的年度电话调查，以评估婴儿护理实践和美国儿科学会关于婴儿睡眠姿势的建议的传播。NISP研究的继续将评估婴儿睡眠实践的趋势和“恢复睡眠”建议的传播，以及影响这些趋势的因素。将努力增加少数民族在已完成的电话中所占的比例，同时使用目前的清单样本。此外，调查人员将补充NISP调查的替代方法，旨在阐明少数群体不遵守的风险因素。最后，将建立基础设施，方便公众访问CHIME和NISP数据集。公众获取服务将包括：(1)维护一个网站，提供有关现有数据的信息以及如何获取这些数据；(2)处理有关数据的查询，并维护跟踪查询进度的数据库；(3)就协助交付所需的数据（即全部或部分数据库）提供咨询；（四）以唯读光碟形式提供资料，并附有适当的文件，以供使用该等资料；（五）在基线支援以外，就数据库的使用提供收费服务谘询。

DESCRIPTION (provided by applicant): The purpose of this project is to continue specific analyses of the Collaborative Home Infant Monitoring Evaluation (CHIME) Study, to continue to conduct the National Infant Sleep Position (NISP) Study, and to serve as a resource for public use datasets from CHIME and NISP, which were developed during the previous grant award period. The CHIME Study enrolled almost 1,100 infants at five university-based clinical sites. The CHIME dataset includes raw and analyzed physiological waveforms from 900,000 hours (300GB) of home monitoring records; 700 overnight polysomnograms; 21,000 cardiorespiratory events exceeding recording thresholds; 6,000 events exceeding conventional alarm thresholds; and 600 events exceeding extreme thresholds. In particular, the proposed analyses of the CHIME data will assess the factors and physiological processes that predict extreme cardiorespiratory events to include early antecedents, developmental patterns, and immediate characteristics of onset and recovery. The NISP Study, begun in 1992, is an annual telephone survey of nighttime caregivers of infants less than eight months of age in the 48 coterminous states to assess infant care practices and dissemination of the AAP recommendation regarding infant sleep position. Continuation of the NISP Study will evaluate trends in infant sleep practices and dissemination of the "Back to Sleep" recommendation, and the factors that influence these trends. Efforts will be made to increase the proportion of minorities in the completed calls, while using the current list sample. Furthermore, the investigators will complement the NISP survey with alternative methodologies designed to illuminate risk factors for non-compliance in minority groups. Finally, an infrastructure will be put in place to facilitate public access to both the CHIME and NISP datasets. The public access service will include: (1) maintaining a website that provide information on the available data and how to obtain it; (2) processing queries regarding the data and maintaining a database that tracks the progress of the requests; (3) providing consultation on the data needed to facilitate the delivery, i.e., all or part of the database; (4) providing the data in CD ROM format with appropriate documentation for use of the data; (5) and providing fee-for-service consultation on the use of the database beyond the baseline support.