Course Development in the Neurobiology of Disease

描述(由申请人提供)： 为响应RFA-MH-05-011(疾病神经生物学课程发展)，我们建议在俄勒冈州健康与科学学院开设疾病神经生物学综合课程 大学的总体目标如下： 1.为研究神经和精神疾病的潜在机制奠定基础。我们的前提是，以主题为导向的方法研究基本的细胞、分子和组织机制，而不是特定于疾病的方法，最能吸引对大脑功能基本方面感兴趣的学生。我们预计，我们不仅可以招募学生参与以疾病为导向的研究，而且我们将使他们成为“随时准备的观察员”，以便更快地注意到他们自己的研究中可能存在的与疾病有关的问题。 2.提供疾病神经生物学中的局部方法和问题的工具箱。这些工具箱会议还将探讨疾病的基本机制和行为表现之间的联系。3.提供神经精神障碍的样本，作为目标1中讨论的主题的培训范例。这些范例将基于OHSU教员的专业知识，但会随着课程的介绍而变化，以使课程保持活力并与学生以及其他受训人员和教职员工相关 4.通过现场患者演示、多媒体演示以及对诊所、医院病房和其他临床环境的访问，提供亲身接触临床情况的机会。这些临床演示将强调动手互动体验，让研究生第一手体验神经和精神疾病对大脑功能的影响，以及对患者、他们的家庭和社区的社会结构的影响。 三项NIH培训拨款使OHSU有资格获得这一RFA：T32NS007466(Gary Banker，PI；T32AA007468 (Christopher Cunningham，PI)和T32AT002688(Barry Oken，PI)。另外三项培训赠款目前已获得资助，除需在2006年9月之前进行竞争性续签外，均符合条件。

DESCRIPTION (provided by applicant): In response to RFA-MH-05-011 (Course Development in the Neurobiology of Disease), we propose the development of an integrated Course in the Neurobiology of Disease at Oregon Health and Science University with the follow general goals: 1. To provide a foundation in the underlying mechanisms of neurological and psychiatric disease. Our premise is that a Theme-oriented approach to fundamental cellular, molecular as well as organismal mechanisms, rather than a disease-specific approach, is best able to engage students who are interested in basic aspects of brain function. We expect that we may not only recruit students into disease-oriented research, but we will make them "ready observers" so that possible disease-related issues in their own research are more quickly noted. 2. To provide a Toolbox of topical methods and issues in the neurobiology of disease. These toolbox sessions will also probe the links between basic mechanisms and behavioral manifestations of disease. 3. To provide a sampling of neuropsychiatric disorders that serve as training examples for the themes discussed in Objective 1. These examples will be based on the expertise of the faculty at OHSU, but will change with each course presentation so that the course remains vibrant and relevant to students, as well as other trainees and faculty 4. To provide hands-on exposure to clinical situations through live patient presentations, multimedia presentations, and visits to clinics, hospital wards, and other clinical settings. These Clinical Demonstrations will stress hands-on interactive experience so that graduate students experience first-hand the impact of neurological and psychiatric disease on brain function, and on the social fabric of the patient's life, their families and their community. Three NIH training grants qualify OHSU for this RFA: T32NS007466 (Gary Banker, PI; T32AA007468 (Christopher Cunningham, PI), and T32AT002688 (Barry Oken, PI). Three other training grants are currently funded and would qualify except that they will be subject to competitive renewal before September 2006.