Gastrointestinal function and appetite in obesity - acute and longer-term effects of changes in energy intake

肥胖症的流行正在呈现流行的比例。虽然减肥饮食有助于人们减肥，但随着时间的推移，尽管继续节食，体重仍会稳定下来。我们的研究提案代表了一项新的倡议，旨在了解胃肠道机制对影响减肥的急性和长期饮食限制的适应。最终，我们的研究将有助于制定长期成功的减肥策略。

The prevalence of obesity is assuming epidemic proportions. While weight loss diets help people to lose weight, body weight stabilises over time despite continued dieting. Our research proposal represents a novel initiative with the aim to understand the adaptations in gastrointestinal mechanisms in response to acute and longer-term dietary restriction that compromise weight loss. Ultimately our research will help to develop weight loss strategies that are successful in the long-term.