COBRE: MUSC: CORE A: RENOVATIONS

描述（由申请人提供）：本提案寻求支持南卡罗来纳医科大学（MUSC）牙科医学院南卡罗来纳口腔健康COBRE的发展。南卡罗来纳口腔健康COBRE将培养一批有针对性的研究人员，他们将成为成熟的研究人员，并将在牙科医学院口腔和颅面健康研究项目的持续发展中提供学术领导。该项目高度利用了MUSC学术健康科学中心的现有优势，包括：1)由NIH研究所和同行评审赞助商合作并提供充足资金的优秀教师导师池；2)一批优秀的有针对性的研究人员，他们与教师导师小组的成员有着牢固的、预先存在的关系；3)关键的相关研究空间和核心资源；4)接触目前正在接受MUSC社区外展项目调查和服务的特殊人群；5)从这些人群获得临床材料；6) MUSC与位于马里兰州贝塞斯达的NIH校园内的NIDCR校内研究项目之间的创新合作关系，为南卡罗来纳州COBRE口腔健康项目的目标研究人员提供更多的研究指导机会。因此，COBRE资助机制将允许牙科医学学院应用COBRE资源，以最有效地满足其研究战略计划的目标，在MUSC开发一个具有全国竞争力和突出的口腔健康研究项目，直接有利于南卡罗来纳州公民的口腔保健需求。南卡罗来纳口腔健康COBRE项目将：*指导最初的五名目标研究人员，以发展成功的、独立的、由美国国立卫生研究院资助的口腔健康科学研究事业。*加强口腔健康研究基础设施。COBRE基金将允许重大开发关键资源（核心），以发展支持MUSC学术健康科学中心多学科口腔健康研究的研究基础设施。*再招聘两名新教员，他们的经验和专业知识将在指导委员会和外部咨询委员会认为至关重要的领域补充COBRE调查员的经验和专业知识。*在最初的5年奖励之后，维持南卡罗来纳州口腔健康COBRE的基础设施。

DESCRIPTION (provided by applicant): This proposal seeks support for the development of the South Carolina COBRE for Oral Health at the Medical University of South Carolina (MUSC) College of Dental Medicine. The South Carolina COBRE for Oral Health will train a cadre of targeted investigators who will become established investigators and will provide academic leadership in the continued development of the College of Dental Medicine's oral and craniofacial health research program. The program is highly leveraged with existing strengths at MUSC's academic health science center including: 1) a pool of outstanding faculty mentors who are collaborative and well-funded by NIH institutes and peer-review sponsors; 2) a pool of outstanding targeted investigators with strong, pre-existing relationships with members of the faculty mentor group; 3) critical relevant research space and core resources; 4) access to unique populations currently under investigation and served by MUSC's community outreach programs; 5) access to clinical materials from these populations; and 6) an innovative collaborative relationship between MUSC and the NIDCR intramural research program on the NIH campus in Bethesda, MD that provides expanded research mentoring opportunities to targeted investigators in the South Carolina COBRE for Oral Health Program. Thus, the COBRE funding mechanism will allow the College of Dental Medicine to apply COBRE resources to most efficiently meet the goals of its research strategic plan to develop a nationally competitive and prominent oral health research program at MUSC which directly benefits the oral health care needs of the citizens of South Carolina. The South Carolina COBRE for Oral Health program will: * Mentor an initial cadre of five targeted investigators to develop successful, independent, NIH- funded research careers in oral health science. * Enhance the oral health research infrastructure. COBRE funds will permit significantdevelopment of critical resources (cores) in the development of a research infrastructure supportive of multidisciplinary oral health research at MUSC's academic health science center. * Recruit two additional new faculty members whose experience and disciplinary expertise will complement those of the COBRE investigators in areas deemed critical by the Steering and the External Advisory Committees. * Sustain the infrastructure of the South Carolina COBRE for Oral Health beyond the initial 5- year award.