Neurobiology of Disease Course at Meharry Medical College/Vanderbilt University

描述（由申请人提供）：本提案概述了梅哈里医学院（MMC）神经科学研究生课程所需的新课程，该课程是与范德比尔特大学医学院（VUMC）授予博士学位的神经科学课程合作开发的，其具体目标是：1）开发疾病神经生物学的研究生课程，重点是帕金森病及相关神经系统疾病，痴呆症，包括阿尔茨海默氏症，成瘾，疼痛，抑郁症及相关情绪障碍，探讨这些疾病的临床和病理表现、这些疾病固有的健康差异、与这些疾病有关的现有临床和行为研究以及这些疾病的分子和细胞基础; 2)开发一门课程，也作为医学生的选修课，参与者在硕士学位， 临床调查科学，临床调查博士学位目前正在MMC开发，博士后研究员，以及类似的学员VUMC，包括VUMC-MMC成瘾精神病学跨学科研究培训计划的研究员; 3）开发基于网络的共享该计划，整体上，以及每年的小型课程，该计划的一个元素供全国参与，CME学分; 4）开发，在与国家认可的评估学者，乔治·皮翁，博士，一个工具，告知在实现其多个但相互依存的目标和该计划的持续发展的课程的有效性协商。本课程的预期和期望的结果是准备学员沿着沿着基础-转化-临床连续体的密集合作，包括鼓励基础科学博士毕业生考虑在转化或临床环境中进行博士后研究，以及临床培训人员将分子工具融入临床和转化研究。由于梅哈里医学院的使命，这门课程将达到相当数量的少数民族学员，从而提高劳动力的多样性，准备将基本发现转化为临床干预措施和最新的假设，关于临床之谜。课程参与者还将更详细地了解这些疾病中每种疾病的健康差异的生物和社会因素。这项建议是在“研究培训联盟”的赞助下提交的， 神经科学”。

DESCRIPTION (provided by applicant): The present proposal outlines a new course required in the graduate program in Neuroscience at Meharry Medical College(MMC), developed in partnership with the PhD-granting Neuroscience program at Vanderbilt University School of Medicine (VUMC) with specific aims to:1) Develop a graduate course in the Neurobiolology of Disease that focuses on Parkinson's disease & related neurological disorders, Dementias including Alzheimer's, Addictions, Pain, and Depression & related mood disorders, addressing the clinical and pathological manifestations of these diseases, the health disparities inherent in these diseases, extant clinical and behavioral research related to these diseases, and the molecular and cellular underpinnings of these diseases; 2) Develop a course that also serves as an elective for medical students, participants in the Masters of Science in Clinical Investigation, the PhD degree in Clinical Investigation currently under development at MMC, postdoctoral fellows , and for similar trainees VUMC, including Fellows in the VUMC-MMC Addiction Psychiatry Interdisciplinary Research Training program; 3) Develop a web-based sharing of this program, in its entirety, and annual mini-courses on one element of this program for national participation, with CME credit; 4) Develop, in consultation with a nationally recognized evaluation scholar, Georgine Pion, PhD, an instrument that informs both the course effectiveness in achieving its multiple but interdependent goals and the continuing evolution of this program. The intended and desired outcome of this course is to prepare trainees for intensive collaborations along the basic-translational-clinical continuum, including encouraging basic science PhD graduates to consider postdoctoral research in a translational or clinical environment, and clinically trained individuals to assimilate molecular tools into their clinical and translational research. Because of the mission of Meharry Medical College, this course will reach a considerable number of minority trainees, thus enhancing the diversity of the workforce prepared to translate basic discoveries into clinical interventions and reciprocally test novel hypotheses regarding clinical enigmas. Course participants also will understand in more detail the biological and social contributors to the health disparities in each of these diseases. This proposal is submitted under the aegis of "The Alliance for Research Training in Neuroscience".