CORE--DATA MANAGEMENT AND STATISTICS

DMSc将提供生物统计、数据处理、数据库编程、研究方法和计算机硬件和软件方面的专业知识，以支持该中心的项目和国家阿尔茨海默氏症协调中心(NACC)的多中心合作活动。该核心将鼓励和促进研究人员之间的合作和各项目之间的信息共享，帮助当地调查人员利用计算资源，监督数据库和开展数据质量活动，为与国家反腐败中心的互动提供接口，并作为集中的生物统计和数据分析资源。该模型是DMSc与项目调查员、核心负责人和合作者之间的共同责任之一，DMSc是中心的集中数据处理资源，项目调查员、核心负责人和合作者在分析自己的测量方面拥有相当的专业知识。DMSc是 负责ADRC数据库，该数据库已被受训人员、国际学者和初级教员用来解决有关AD和其他痴呆症的行为变化的问题，在1999-2002年的当前赠款期间发表了36篇论文。数据管理信息中心将继续提供所有数据录入、备份、文件和其他数据库服务，并将及时和准确地向国家反腐败委员会和其他外部机构提交报告。将向研究人员提供复杂的生物统计学和方法学支助，以帮助规划和执行数据分析，并协助设计和实施新的研究项目。核心成员将参与审查亚洲发展研究中心的试点研究。青年科学家的发展将通过讲授报告和研究项目的个人指导来完成。

The DMSC will provide expertise in biostatistics, data processing, database programming, research methodology and computer hardware and software to support the Center's projects and the multi-center collaborative activities of the National Alzheimer's Coordinating Center (NACC). The Core will encourage and facilitate collaborations among researchers and the sharing of information across projects, help local investigators make use of computing resources, oversee the database and perform data quality activities, provide the interface for interactions with the NACC, and serve as a centralized biostatistical and data analysis resource. The model is one of shared responsibilities between the DMSC, which is the centralized data processing resource in the Center, and the project investigators, core chiefs, and collaborators who have considerable expertise in analysis of their own measures. The DMSC is responsible for the ADRC database, which has been used by trainees, international scholars, and junior faculty to address questions regarding behavioral changes in AD and other dementias to produce 36 papers in the current grant period 1999-2002. The DMSC will continue to perform all data entry, backup, documentation and other database services, and will make timely and accurate submissions to NACC and other external agencies. Sophisticated biostatistical and methodological support will be provided to researchers to help in planning and execution of data analyses and to aid in the design and implementation of new research projects. Members of the Core will participate in review of ADRC pilot studies. Development of young scientists will be accomplished through didactic presentations and individual mentoring on research projects.