Pharmaceutical Salts and Their Hydrates
Pharmaceutical Salts and Their Hydrates
批准号:
2888681
负责人:
金额:
$0.0万
依托单位:
依托单位国家:
英国
项目类别:
Studentship
财政年份:
2023
资助国家:
英国
项目状态:
未结题
起止时间:
2023 至 --
中文摘要
药物通常以盐的形式提供,因为它们的溶解度曲线得到了改善。然而,盐比固体形式的中性成分更有可能水合。在这个项目中,我们试图从结构的角度更好地理解药物盐的水化倾向,使用从数据库分析到实验的组合方法。
英文摘要
Drugs are often delivered as salts because of their improved solubility profiles. Salts, however, are more likely to be hydrated than solid forms of neutral components. In this project, we seek to better understand the hydration propensity of pharmaceutical salts from a structural viewpoint using a combination of approaches from database analyses to experimentation.
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