Design and Synthesis of New Chiral Heterogeneous Photocatalysts for Light-Driven Asymmetric Organocatalysis

光氧化还原催化是有机合成中的一个重要进展，它在温和的条件下提供了不同的反应途径。具有对映体选择性的光氧化还原反应的能力特别重要，2021年诺贝尔化学奖因不对称有机催化的发展而获得。大多数合成化学家可用的光催化剂都是均相金属络合物或有机染料，这带来了成本、可回收性和废物产生的问题。多相有机光催化剂的开发可以解决其中的许多问题，但其在有机合成中的应用还处于起步阶段，还不够发达。在这个项目中，我们的目标是设计和合成新型手性多相光催化剂，用于光驱动的不对称有机催化。

Photoredox catalysis is an important development in organic synthesis, offering distinct reaction pathways under mild conditions. The ability to perform photoredox reactions with enantioselectivity is particularly important, as highlighted by the award of the 2021 Nobel prize in Chemistry for the development of asymmetric organocatalysis. Most photocatalysts available to synthetic chemists are homogeneous metal-complexes or organic dyes, which raise issues of cost, recyclability, and waste production. Development of heterogeneous organic photocatalysts could address many of these issues but their application in organic synthesis is still in its infancy and underdeveloped. In this project we aim to design and synthesise new chiral heterogeneous photocatalysts for light-driven asymmetric organocatalysis.