Alcohol Intervention/Treatment Outcome Research Training

项目描述（申请人提供）：本项目旨在培养博士后生物医学、行为学、卫生保健和其他公共卫生科学家，从事酒精滥用和酒精中毒治疗方面的研究。首要目标是提高我们的学员推进酒精滥用治疗研究所需的关键科学推理技能。从我们的角度来看，此类研究将受益于采用多学科框架（包括干预发生的生物、心理、社会和文化背景）的复杂和充分发展的理论指导下的干预措施。虽然其他机构的培训项目可能涉及治疗/早期干预研究，但这是本博士后项目的主要任务。我们培训项目的显著特点是：跨学科；关于与酒精或药物滥用有关的功能障碍的性质，它不接受单一的意识形态或理论；它为干预研究的各个层面提供培训；它将预防、早期干预和治疗视为一个连续统一体；它还为受训人员提供了高度个性化的机会，使他们对酒精/药物相关功能障碍的知识基础有所贡献，并知道如何应对。研究员的培训项目通常为两年，但有时我们也会将培训时间延长至三年。该项目平均每年招收四名新研究员。培训经验的结构是提供个性化的研究经验和培训，辅以共同的学术课程，其中分配了20%的研究员培训时间。课程涵盖四个不同的领域：(1)统计/研究方法；(2) grantsmanship;(3)研究中的伦理问题；(4)为期两年的酒精专题研讨会。研究员的个人研究培训经历来自于研究员制定的计划，并得到他/她的导师的同意。该计划主要强调临床试验培训，其次强调将临床研究转化为服务研究。最近增加的神经生物学和行为遗传学的教学和研究经验，扩大了我们在即将到来的周期中从基础到临床研究的转化研究的重点。

DESCRIPTION (provided by applicant): The aim of our program is to train post-doctoral biomedical, behavioral, health care and other public health scientists to do research on treatment for alcohol abuse and alcoholism. An overarching goal is to enhance the critical scientific reasoning skills needed for our trainees to advance treatment research in alcohol abuse. From our perspective such research will benefit from interventions guided by sophisticated and fully developed theory using a multidisciplinary framework that includes the biological, psychological, social and cultural context in which interventions occur. While other institutional training programs may address treatment/early intervention research, this is the primary mission for this post-doctoral program. Distinctive features of our training program are: that it is interdisciplinary; that it embraces no single ideology or theory concerning the nature of dysfunctions related to alcohol or drug abuse; that it provides training at each level of intervention research; that it views prevention, early intervention and treatment along a continuum; and that it provides trainees with highly individualized opportunities to contribute to the knowledge base of alcohol/drug-related dysfunction and what to do about it. The training program for fellows is typically two years but on occasion we extend this training period for three years. The program accepts on average four new fellows per year. The training experience is structured to provide individualized research experience and training, complemented by a common academic curriculum to which 20% of fellows' training time is allocated. Four distinct areas are covered in the curriculum: (1) statistics/research methodology; (2) grantsmanship; (3) ethical issues in research; and (4) a two-year series of alcohol-specific seminars. The fellow's individual research training experience emerges from a plan developed by the fellow and agreed to by his/her mentors. The program has a primary emphasis on training in clinical trials with a secondary emphasis on the translation of clinical research into services research. The recent addition of neurobiology and behavioral genetics didactic and research experiences expands our focus of translational research from basic to clinical research in this upcoming cycle.