Family-Based HIV Prevention for Latinos

描述（由申请人提供）：拉丁美洲人在被诊断患有艾滋病毒的青少年中所占的比例不成比例，拉丁裔青少年有从事可能导致艾滋病毒的性行为的风险。然而，与其他族裔群体不同，拉丁裔青少年的艾滋病毒预防干预措施的数据迄今尚未公布。这个K奖将专门针对拉丁裔家庭进行以家庭为基础的干预的初步研究。在NIMH少数族裔补充奖的支持下，Lescano博士从一项针对非少数族裔青年的多地点试验中改编了一种基于家庭的干预方法。采用定性方法，Lescano博士在干预中增加了与拉丁美洲人相关的家庭背景问题，如文化适应、宗教信仰、性别角色和性社会化、亲子沟通和监测实践。“K奖”的初始阶段将是经过调整的以家庭为基础的干预措施，包括三个队列（每组8个家庭），以进一步评估参与者的反应和适当性。然后，干预措施将根据使用结构化离职面谈的反馈进行修订。接下来，100个有13至18岁青少年的拉丁裔家庭将被随机分为以家庭为基础的艾滋病毒预防干预组和以饮食和锻炼等健康行为为重点的一般健康促进组（GHP）。小组由6至8名家长和青少年组成，参加为期一天，7小时的讲习班。这两种干预措施分别针对青年和父母开展活动（例如，关注青少年的脆弱性），同时针对父母和青少年开展活动。该项目将通过评估青少年与艾滋病毒相关的性行为和态度、性别和性社会化、亲子沟通和父母监测的变化来估计拉丁裔家庭艾滋病毒预防干预的效果大小。措施将在基线和干预后3个月和6个月完成。在这个K奖中所做的工作将提供试点数据，将导致提交R01，以确定在更大的拉丁裔样本中，与仅针对青少年的、基于技能的艾滋病毒预防组和一般健康促进组相比，干预措施的有效性。拉丁裔社区迫切需要有效的干预措施。

DESCRIPTION (provided by applicant): Latinos are disproportionately represented among those diagnosed with HIV and Latino adolescents are at risk for engaging in sexual behaviors that can lead to HIV. However, data regarding HIV prevention interventions for Latino adolescents, as distinct from other ethnic groups, have not been published to date. This K Award will conduct an initial study of a family-based intervention specifically for Latino families. With the support of a NIMH Minority Supplement Award, Dr. Lescano has adapted a family-based intervention from a multi-site trial for non-minority youth. Using a qualitative approach, Dr. Lescano has added to the intervention family context issues relevant to Latinos such as acculturation, religiosity, gender role and sexual socialization, parent-child communication, and monitoring practices. The initial phase of the K Award will be a run-through of the adapted family-based intervention with three cohorts (8 families per group) to further assess participant reaction and appropriateness. The intervention will then be revised based on feedback using structured exit interviews. Next, 100 Latino families with an adolescent between the ages of 13 and 18 will be randomized into either the family based HIV prevention intervention or a general health promotion (GHP) condition that focuses on healthy behaviors such as diet and exercise. Groups consist of 6 to 8 parent and youth dyads in a one-day, 7-hour workshop. Both interventions employ activities for youth and parents separately (e.g., focus on adolescent vulnerability) and parents and adolescents together. The project will estimate the effect size of the Latino Family-based HIV prevention intervention from assessment of changes in the adolescents' HIV-related sexual behavior and attitudes, gender and sexual socialization, parent-child communication, and parental monitoring. Measures will be completed at baseline and at 3 and 6 months post-intervention. The work done in this K Award will provide pilot data that will lead to submission of an R01 to determine the efficacy of the intervention, compared to a adolescent-only, skills-based HIV prevention group and a general health promotion group, in a larger sample of Latinos. An efficacious intervention is urgently needed for Latino communities.